Protein: KAPB
cAMP-dependent protein kinase type 2 (PKA 2) (EC 2.7.11.11)

Gene: KAPB, TPK2
Organism: Saccharomyces cerevisiae S288C
Interactions: 107
UniProt ID: P06245

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000932 - P-body
GO:0001403 - invasive growth in response to glucose limitation
GO:0004672 - protein kinase activity
GO:0004691 - cAMP-dependent protein kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

441311

KAPR
cAMP-dependent protein kinase regulatory subunit

19

20

Small-scale

0.988

High

437859

KAPC
cAMP-dependent protein kinase type 3

8

16

Small-scale

0.968

High

440992

KAPA
cAMP-dependent protein kinase type 1

8

14

Small-scale

0.966

High

441348

RPB7
DNA-directed RNA polymerase II subunit RPB7

3

1

Small-scale

0.847

High

441317

YAK1
Dual specificity protein kinase YAK1

2

15

High-throughput

0.799

High

441309

KAPB
cAMP-dependent protein kinase type 2

2

16

High-throughput

0.757

High

441393

PKH1
Serine/threonine-protein kinase PKH1

1

17

Small-scale

0.724

High

441324

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

1

High-throughput

0.691

High

441330

KC11
Casein kinase I homolog 1

1

16

High-throughput

0.691

High

441347

MSN4
Zinc finger protein MSN4

1

4

High-throughput

0.691

High

441360

KSP1
Serine/threonine-protein kinase KSP1

1

17

High-throughput

0.691

High

441349

HSL1
Probable serine/threonine-protein kinase HSL1

1

14

High-throughput

0.665

High

441355

CHK1
Serine/threonine-protein kinase CHK1

1

2

High-throughput

0.665

High

441319

PHO85
Cyclin-dependent protein kinase PHO85

1

8

High-throughput

0.647

High

441329

KCC2
Calcium/calmodulin-dependent protein kinase II

1

6

High-throughput

0.647

High

441333

MEK1
Meiosis-specific serine/threonine-protein kinase MEK1

1

14

High-throughput

0.647

High

441336

KCC1
Calcium/calmodulin-dependent protein kinase I

1

9

High-throughput

0.647

High

441350

WHI3
Protein WHI3

1

2

Small-scale

0.647

High

441354

AKL1
Serine/threonine-protein kinase AKL1

1

13

High-throughput

0.647

High

441362

RIM4
Meiotic activator RIM4

1

10

High-throughput

0.647

High

441375

AZF1
Transcription factor AZF1

1

2

High-throughput

0.647

High

403299

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

9

Small-scale

0.618

High

441318

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

2

High-throughput

0.611

High

441323

SFL1
Flocculation suppression protein

2

3

Small-scale

0.609

High

441384

MGA1
Protein MGA1

2

2

Small-scale

0.594

High

441322

HSP60
Heat shock protein 60, mitochondrial

2

17

High-throughput

0.584

High

441340

TREA
Cytosolic neutral trehalase

2

2

Small-scale

0.565

High

441382

JHD2
Histone demethylase JHD2

1

3

Small-scale

0.561

High

441371

SIP5
Protein SIP5

2

1

High-throughput

0.550

High

364863

KPYK1
Pyruvate kinase 1

1

4

Small-scale

0.536

High

441383

KPYK2
Pyruvate kinase 2

1

4

Small-scale

0.536

High

401811

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

2

High-throughput

0.536

High

416841

CDC25
Cell division control protein 25

1

4

High-throughput

0.536

High

441310

SYTM
Threonine--tRNA ligase, mitochondrial

1

1

High-throughput

0.536

High

441312

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

4

High-throughput

0.536

High

441327

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

1

High-throughput

0.536

High

441328

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

1

High-throughput

0.536

High

441332

SPT6
Transcription elongation factor SPT6

1

1

High-throughput

0.536

High

441337

SPT5
Transcription elongation factor SPT5

1

2

High-throughput

0.536

High

441338

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

1

High-throughput

0.536

High

441344

PMD1
Negative regulator of sporulation PMD1

1

1

High-throughput

0.536

High

441351

TAF14
Transcription initiation factor TFIID subunit 14

1

1

High-throughput

0.536

High

441363

RPB11
DNA-directed RNA polymerase II subunit RPB11

1

1

High-throughput

0.536

High

441376

T2FA
Transcription initiation factor IIF subunit alpha

1

1

High-throughput

0.536

High

441385

MDS3
Negative regulator of sporulation MDS3

1

1

High-throughput

0.536

High

441396

IWS1
Transcription factor SPN1

1

2

High-throughput

0.536

High

441402

YP247
WD repeat-containing protein YPL247C

1

8

High-throughput

0.536

High

441365

GPB2
Guanine nucleotide-binding protein subunit beta 2

1

2

Small-scale

0.527

High

441325

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

High-throughput

0.513

High

441326

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.513

High

441369

RTR1
RNA polymerase II subunit B1 CTD phosphatase RTR1

1

0

High-throughput

0.513

High

441372

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.513

High

441377

T2FB
Transcription initiation factor IIF subunit beta

1

0

High-throughput

0.513

High

441381

GPN1
GPN-loop GTPase 1

1

0

High-throughput

0.513

High

441321

IRA2
Inhibitory regulator protein IRA2

1

8

Small-scale

0.501

High

441334

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

3

Small-scale

0.501

High

441341

SMY1
Kinesin-related protein SMY1

1

5

High-throughput

0.501

High

441343

PAH1
Phosphatidic acid phosphohydrolase 1

1

2

Small-scale

0.501

High

441345

RGT1
Glucose transport transcription regulator RGT1

1

2

Small-scale

0.501

High

441353

PUR92
Bifunctional purine biosynthesis protein ADE17 [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase

1

1

High-throughput

0.501

High

441359

IF5
Eukaryotic translation initiation factor 5

1

4

Small-scale

0.501

High

441364

DHH1
ATP-dependent RNA helicase DHH1

1

14

Small-scale

0.501

High

441373

6P21
6-phosphofructo-2-kinase 1

1

7

High-throughput

0.501

High

441379

IDS2
IME2-dependent-signaling protein

1

1

High-throughput

0.501

High

441386

PDK2
[Pyruvate dehydrogenase

1

7

High-throughput

0.501

High

441399

STB3
Protein STB3

1

1

High-throughput

0.501

High

367645

ENO1
Enolase 1

1

3

High-throughput

0.500

High

404997

LEU3
3-isopropylmalate dehydrogenase

1

2

High-throughput

0.500

High

439182

PDC1
Pyruvate decarboxylase isozyme 1

1

1

High-throughput

0.500

High

441361

YHI0
Putative proline--tRNA ligase YHR020W

1

2

High-throughput

0.500

High

441366

SAHH
Adenosylhomocysteinase

1

2

High-throughput

0.500

High

441368

IMB4
Importin subunit beta-4

1

4

High-throughput

0.500

High

441367

GIP2
GLC7-interacting protein 2

1

2

High-throughput

0.489

High

438232

NOT3
General negative regulator of transcription subunit 3

1

1

Small-scale

0.481

High

441401

NOT5
General negative regulator of transcription subunit 5

1

1

Small-scale

0.481

High

441314

PCKA
Phosphoenolpyruvate carboxykinase

1

0

High-throughput

0.480

High

441394

KYNU
Kynureninase

1

0

High-throughput

0.480

High

441397

PEX19
Peroxisomal membrane protein import receptor PEX19

1

0

High-throughput

0.480

High

441398

CLP1
mRNA cleavage and polyadenylation factor CLP1

1

0

High-throughput

0.480

High

441400

PEX11
Peroxisomal membrane protein PMP27

1

0

High-throughput

0.480

High

441316

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.479

High

434684

RS3
Small ribosomal subunit protein uS3

1

2

Small-scale

0.479

High

441335

CDC20
APC/C activator protein CDC20

1

6

Small-scale

0.479

High

441346

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

441356

ATG8
Autophagy-related protein 8

1

1

High-throughput

0.479

High

441395

NHEJ1
Non-homologous end-joining protein 1

1

1

Small-scale

0.479

High

441320

GAP1
General amino-acid permease GAP1

1

4

Small-scale

0.457

High

441331

MBR1
Mitochondrial biogenesis regulation protein 1

1

2

High-throughput

0.457

High

441339

DGR2
2-deoxy-glucose resistant protein 2

1

6

High-throughput

0.457

High

441342

ISF1
Increasing suppression factor 1

1

2

High-throughput

0.457

High

441352

MNR2
Manganese resistance protein MNR2

1

4

High-throughput

0.457

High

441378

IGD1
Inhibitor of glycogen debranching 1

1

2

High-throughput

0.457

High

441380

AVT1
Vacuolar amino acid transporter 1

1

4

High-throughput

0.457

High

441388

YIF1
Protein transport protein YIF1

1

3

High-throughput

0.457

High

441390

YP077
Uncharacterized protein YPL077C

1

1

High-throughput

0.457

High

441391

NGL3
Probable RNA exonuclease NGL3

1

1

High-throughput

0.457

High

441392

ADD37
Alpha1-proteinase inhibitor-degradation deficient protein 37

1

2

High-throughput

0.457

High

441389

UBC7
Ubiquitin-conjugating enzyme E2 7

1

1

High-throughput

0.457

High

441313

HSP72
Heat shock protein SSA2

1

13

High-throughput

0.445

High

441315

SSB1
Ribosome-associated molecular chaperone SSB1

1

13

High-throughput

0.445

High

441370

SSB2
Ribosome-associated molecular chaperone SSB2

1

13

High-throughput

0.445

High

441358

YB75
Uncharacterized protein YBR225W

1

0

High-throughput

0.279

Low

441357

FTH1
Iron transporter FTH1

1

0

High-throughput

0.261

Low

441374

SNL1
HSP70 co-chaperone SNL1

1

0

High-throughput

0.261

Low

441387

DAM1
DASH complex subunit DAM1

1

0

Small-scale

0.261

Low

439056

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

0

High-throughput

0.261

Low


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Last updated: 11Aug2025