HitPredict

Interactor 1: TX1B3 (O14907)
Tax1-binding protein 3 (Glutaminase-interacting protein 3) (Tax interaction protein 1) (TIP-1) (Tax-interacting protein 1)
Gene: TAX1BP3

Interactor 2: APC (P25054)
Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5)
Gene: APC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008013 - beta-catenin binding GO:0008285 - negative regulation of cell population proliferation GO:0016055 - Wnt signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 124 Hs			1 2843
+	Mm
		1193533 SCRIB_MOUSE (11-108): 3.74e-20: 86.6: 25.25		Q8BNP7_MOUSE (1-1058): 0: 1478: 95.09
+	Hs
		626254 LIN7B_HUMAN (10-123): 3.41e-27: 101: 24.35		APC_HUMAN (1-2843): 0: 1316: 100.00
+	Hs
		626266 LIN7C_HUMAN (10-124): 7.55e-27: 100: 25.00		APC_HUMAN (1-2843): 0: 1316: 100.00
+	Hs
		626233 ERBIN_HUMAN (1-110): 1.42e-23: 96.3: 36.21		APC_HUMAN (1-2843): 0: 1316: 100.00
+	Rn
		677772 DLG4_RAT (6-111): 6.02e-22: 91.6: 31.78		APC_RAT (1-2843): 0: 1222: 89.60
+	Mm
		1142526 DLG4_MOUSE (11-111): 4.01e-22: 92: 33.33		APC_MOUSE (1-2843): 0: 1220: 89.82
+	Mm
		57254 A2AKD7_MOUSE (5-121): 2.19e-28: 109: 26.27		NACAM_MOUSE (703-2637): 1.09e-53: 211: 8.91
+	Hs
		653971 SNTA1_HUMAN (5-121): 3.75e-28: 108: 26.27		MAP4_HUMAN (2119-2724): 1.19e-29: 131: 15.90
+	Hs
		654033 SNX27_HUMAN (16-124): 8.53e-27: 105: 20.00		MAP4_HUMAN (2119-2724): 1.19e-29: 131: 15.90
+	Hs
		653989 PDZ11_HUMAN (3-121): 1.66e-26: 97.7: 22.69		MAP4_HUMAN (2119-2724): 1.19e-29: 131: 15.90
+	Hs
		654037 ERBIN_HUMAN (1-110): 1.42e-23: 96.3: 36.21		MAP4_HUMAN (2119-2724): 1.19e-29: 131: 15.90
+	Hs
		1056856 PDZ11_HUMAN (3-121): 1.66e-26: 97.7: 22.69		MDC1_HUMAN (1750-2784): 3.28e-21: 104: 11.74
+	Mm
		1143541 DLG4_MOUSE (11-111): 4.01e-22: 92: 33.33		MAP1A_MOUSE (738-2466): 8.19e-18: 93.6: 8.21
+	Hs
		944681 DLG2_HUMAN (16-115): 4.73e-22: 92: 29.41		MAP1A_HUMAN (907-2836): 5.17e-16: 87.6: 8.68
+	Mm
		1143421 DLG4_MOUSE (11-111): 4.01e-22: 92: 33.33		ANK2_MOUSE (1056-2841): 1.1e-15: 86.5: 9.74
+	Hs
		942322 DLG4_HUMAN (11-111): 1.16e-20: 87.7: 34.31		MAP1A_HUMAN (907-2836): 5.17e-16: 87.6: 8.68
+	Rn
		677763 DLG4_RAT (6-111): 6.02e-22: 91.6: 31.78		MAP1A_RAT (823-2474): 2.27e-13: 78.8: 8.11
+	Rn
		713908 DLG2_RAT (16-115): 5.73e-22: 91.6: 28.43		MAP1A_RAT (823-2474): 2.27e-13: 78.8: 8.11
+	Hs
		1186084 SNX27_HUMAN (16-124): 8.53e-27: 105: 20.00		MICA3_HUMAN (1200-1800): 2.91e-09: 65.2: 13.62
+	Ce
		246631 TX1B3_CAEEL (3-116): 7.56e-27: 98.1: 42.02		O61201_CAEEL (1675-2838): 2.4e-10: 69.1: 10.06