Protein: MUSK
Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1) (Muscle-specific tyrosine-protein kinase receptor) (MuSK) (Muscle-specific kinase receptor)

Gene: MUSK
Organism: Homo sapiens
Interactions: 70
UniProt ID: O15146

Gene Ontology (top 5):
GO:0001934 - positive regulation of protein phosphorylation
GO:0004713 - protein tyrosine kinase activity
GO:0004714 - transmembrane receptor protein tyrosine kinase activity
GO:0005524 - ATP binding
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

179592

HS90A
Heat shock protein HSP 90-alpha

2

20

High-throughput

0.754

High

179629

ERBIN
Erbin

1

20

Small-scale

0.740

High

179622

SYNE1
Nesprin-1

1

14

Small-scale

0.713

High

179612

CDC37
Hsp90 co-chaperone Cdc37

2

20

High-throughput

0.705

High

179595

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

20

High-throughput

0.691

High

179593

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.665

High

179584

DJC13
DnaJ homolog subfamily C member 13

2

20

High-throughput

0.628

High

179636

RBNS5
Rabenosyn-5

2

14

High-throughput

0.628

High

179646

ADA30
Disintegrin and metalloproteinase domain-containing protein 30

2

11

High-throughput

0.628

High

179609

SCRIB
Protein scribble homolog

1

20

Small-scale

0.618

High

179616

Q6PK50
HSP90AB1 protein

1

20

High-throughput

0.618

High

179619

VRK2
Serine/threonine-protein kinase VRK2

1

20

High-throughput

0.618

High

179649

S23IP
SEC23-interacting protein

1

18

High-throughput

0.618

High

179591

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

20

High-throughput

0.575

High

67584

RHG32
Rho GTPase-activating protein 32

1

20

High-throughput

0.553

High

179596

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

20

High-throughput

0.553

High

179597

1433S
14-3-3 protein sigma

1

20

High-throughput

0.553

High

179602

1433E
14-3-3 protein epsilon

1

6

High-throughput

0.553

High

179607

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

19

High-throughput

0.553

High

179618

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

1

5

High-throughput

0.553

High

179633

LRRC1
Leucine-rich repeat-containing protein 1

1

20

Small-scale

0.553

High

179635

ILKAP
Integrin-linked kinase-associated serine/threonine phosphatase 2C

1

20

High-throughput

0.541

High

179623

STYX
Serine/threonine/tyrosine-interacting protein

1

20

High-throughput

0.494

High

179588

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

20

High-throughput

0.479

High

179603

RACK1
Small ribosomal subunit protein RACK1

1

11

High-throughput

0.479

High

179604

CKAP4
Cytoskeleton-associated protein 4

1

12

High-throughput

0.479

High

179608

STIM1
Stromal interaction molecule 1

1

19

High-throughput

0.479

High

179614

CDKAL
Threonylcarbamoyladenosine tRNA methylthiotransferase

1

5

High-throughput

0.479

High

179620

ARFG2
ADP-ribosylation factor GTPase-activating protein 2

1

20

High-throughput

0.479

High

179626

TTC17
Tetratricopeptide repeat protein 17

1

1

High-throughput

0.479

High

179627

ASTRA
Protein Aster-A

1

1

High-throughput

0.479

High

179634

NDC1
Nucleoporin NDC1

1

3

High-throughput

0.479

High

179638

GORS2
Golgi reassembly-stacking protein 2

1

13

High-throughput

0.479

High

179639

JPH1
Junctophilin-1

1

8

High-throughput

0.479

High

179643

NSMA3
Sphingomyelin phosphodiesterase 4

1

2

High-throughput

0.479

High

179644

VAPA
Vesicle-associated membrane protein-associated protein A

1

20

High-throughput

0.479

High

179647

PZRN3
E3 ubiquitin-protein ligase PDZRN3

1

20

Small-scale

0.479

High

179605

LG3BP
Galectin-3-binding protein

1

15

High-throughput

0.457

High

179632

ERP44
Endoplasmic reticulum resident protein 44

1

20

High-throughput

0.457

High

71676

NUD19
Acyl-coenzyme A diphosphatase NUDT19

1

6

High-throughput

0.437

High

158053

COPE
Coatomer subunit epsilon

1

7

High-throughput

0.437

High

179583

USO1
General vesicular transport factor p115

1

13

High-throughput

0.437

High

179585

SC22B
Vesicle-trafficking protein SEC22b

1

12

High-throughput

0.437

High

179586

TACC1
Transforming acidic coiled-coil-containing protein 1

1

20

High-throughput

0.437

High

179587

SC31A
Protein transport protein Sec31A

1

20

High-throughput

0.437

High

179589

SC24A
Protein transport protein Sec24A

1

20

High-throughput

0.437

High

179590

SC24B
Protein transport protein Sec24B

1

20

High-throughput

0.437

High

179594

SRPRA
Signal recognition particle receptor subunit alpha

1

18

High-throughput

0.437

High

179598

COPB2
Coatomer subunit beta'

1

16

High-throughput

0.437

High

179599

COPD
Coatomer subunit delta

1

8

High-throughput

0.437

High

179600

EMD
Emerin

1

15

High-throughput

0.437

High

179601

AL3A2
Aldehyde dehydrogenase family 3 member A2

1

15

High-throughput

0.437

High

179606

STX5
Syntaxin-5

1

10

High-throughput

0.437

High

179610

SC23A
Protein transport protein Sec23A

1

20

High-throughput

0.437

High

179611

SC23B
Protein transport protein Sec23B

1

20

High-throughput

0.437

High

179615

CEP85
Centrosomal protein of 85 kDa

1

20

High-throughput

0.437

High

179621

KRI1
Protein KRI1 homolog

1

12

High-throughput

0.437

High

179624

SCFD1
Sec1 family domain-containing protein 1

1

20

High-throughput

0.437

High

179625

TFG
Protein TFG

1

20

High-throughput

0.437

High

179628

ZN512
Zinc finger protein 512

1

4

High-throughput

0.437

High

179630

CLCC1
Chloride channel CLIC-like protein 1

1

10

High-throughput

0.437

High

179631

TM209
Transmembrane protein 209

1

4

High-throughput

0.437

High

179637

GCP60
Golgi resident protein GCP60

1

13

High-throughput

0.437

High

179640

APMAP
Adipocyte plasma membrane-associated protein

1

3

High-throughput

0.437

High

179641

ARFG3
ADP-ribosylation factor GTPase-activating protein 3

1

20

High-throughput

0.437

High

179642

AAAS
Aladin

1

20

High-throughput

0.437

High

179645

DJB11
DnaJ homolog subfamily B member 11

1

20

High-throughput

0.437

High

179648

TNR6B
Trinucleotide repeat-containing gene 6B protein

1

3

High-throughput

0.437

High

179613

TM201
Transmembrane protein 201

1

0

High-throughput

0.249

Low

179617

UBP54
Ubiquitin carboxyl-terminal hydrolase 54

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025