HitPredict

Interactor 1: HGS (O14964)
Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) (Protein pp110)
Gene: HGS

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	30166454, 35063084
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0035091 - phosphatidylinositol binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 777 Hs			1 758
+	Hs
		497214 TM1L2_HUMAN (5-448): 6.41e-50: 185: 17.17		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497381 STAM1_HUMAN (4-172): 1.45e-42: 164: 28.40		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497715 ANFY1_HUMAN (156-219): 2.38e-14: 79.3: 50.00		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Dm
		54321 HRS_DROME (6-672): 1.2e-54: 203: 35.98		A1Z9J3_DROME (14-746): 5.58e-33: 139: 11.47
+	Hs
		203256 ANFY1_HUMAN (156-219): 2.38e-14: 79.3: 50.00		SYNJ1_HUMAN (7-411): 1.53e-09: 63.9: 9.76
+	Mm
		1351630 PCLO_MOUSE (227-739): 8.86e-09: 61.6: 11.93		PCLO_MOUSE (6-742): 3.27e-11: 69.3: 9.66