Interactor 1: HGS (O14964)
Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) (Protein pp110)
Gene: HGS
Interactor 2: STAM1 (Q92783)
Signal transducing adapter molecule 1 (STAM-1)
Gene: STAM
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.988 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9407053, 35271311, 13679051, 24790097, 16189514, 20736164, 28514442, 29604273, 29892012, 32296183, 33961781, 20505072, 24344129, 19278655, 31515488, unassigned1304 |
| Identification Methods | affinity chromatography technology, two hybrid, pull down, molecular sieving, x-ray crystallography, light scattering, dynamic light scattering, cosedimentation in solution, two hybrid array, two hybrid prey pooling approach and 3 others
more... |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | FYVE~VHS, VHS~VHS |
| Common GO terms | GO:0005829 - cytosol GO:0007165 - signal transduction GO:0016236 - macroautophagy GO:0031901 - early endosome membrane GO:0033565 - ESCRT-0 complex and 7 others more... |
| Homologous interactions | 16 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
