Interactor 1: HGS (O14964)
Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) (Protein pp110)
Gene: HGS

Interactor 2: MB12A (Q96EY5)
Multivesicular body subunit 12A (CIN85/CD2AP family-binding protein) (ESCRT-I complex subunit MVB12A) (Protein FAM125A)
Gene: MVB12A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.536

The method score is based on:

Property Details
Experiments 35271311
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0016236 - macroautophagy
GO:0036258 - multivesicular body assembly
GO:0043130 - ubiquitin binding
GO:0043328 - protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
and 2 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 777
Hs

1 273
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024