Protein: CHD2
Chromodomain-helicase-DNA-binding protein 2 (CHD-2) (EC 3.6.4.-) (ATP-dependent helicase CHD2)

Gene: CHD2
Organism: Homo sapiens
Interactions: 69
UniProt ID: O14647

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0003723 - RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

160197

TRI41
E3 ubiquitin-protein ligase TRIM41

2

1

High-throughput

0.739

High

160170

H2BFS
Histone H2B type F-S

1

20

High-throughput

0.665

High

160211

TRIM1
Probable E3 ubiquitin-protein ligase MID2

1

9

High-throughput

0.662

High

160150

EED
Polycomb protein EED

1

20

High-throughput

0.618

High

160158

H2A1B
Histone H2A type 1-B/E

1

20

High-throughput

0.618

High

160171

H4
Histone H4

1

11

High-throughput

0.618

High

160175

H33
Histone H3.3

1

20

High-throughput

0.618

High

160202

UHRF2
E3 ubiquitin-protein ligase UHRF2

1

17

Small-scale

0.618

High

160204

DDX23
Probable ATP-dependent RNA helicase DDX23

1

15

High-throughput

0.618

High

160207

DDX21
Nucleolar RNA helicase 2

1

15

High-throughput

0.618

High

160180

CD166
CD166 antigen

3

1

High-throughput

0.585

High

160148

BRD4
Bromodomain-containing protein 4

2

20

High-throughput

0.584

High

160196

ZN398
Zinc finger protein 398

2

0

High-throughput

0.580

High

160181

DHX8
ATP-dependent RNA helicase DHX8

1

10

High-throughput

0.575

High

160192

BEND7
BEN domain-containing protein 7

1

1

High-throughput

0.573

High

160209

THAP1
THAP domain-containing protein 1

1

2

High-throughput

0.573

High

160154

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

160191

ELOA2
Elongin-A2

2

3

High-throughput

0.553

High

160205

TRI54
Tripartite motif-containing protein 54

2

8

High-throughput

0.553

High

160186

RN123
E3 ubiquitin-protein ligase RNF123

1

14

High-throughput

0.553

High

160188

TRI67
Tripartite motif-containing protein 67

1

9

High-throughput

0.553

High

160174

SRPK2
SRSF protein kinase 2

1

8

High-throughput

0.550

High

160200

TEKT1
Tektin-1

1

0

High-throughput

0.549

High

160149

TULP3
Tubby-related protein 3

1

1

High-throughput

0.541

High

160178

SSRP1
FACT complex subunit SSRP1

1

20

High-throughput

0.536

High

160161

FLNA
Filamin-A

1

3

High-throughput

0.515

High

160182

SMC1A
Structural maintenance of chromosomes protein 1A

1

6

High-throughput

0.515

High

160187

Q6FHY5
MEOX2 protein

1

3

High-throughput

0.515

High

160190

KMT5C
Histone-lysine N-methyltransferase KMT5C

1

0

High-throughput

0.513

High

160167

MEOX2
Homeobox protein MOX-2

1

3

High-throughput

0.481

High

156688

CTRO
Citron Rho-interacting kinase

1

7

High-throughput

0.479

High

160147

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

9

High-throughput

0.479

High

160151

KI20A
Kinesin-like protein KIF20A

1

14

High-throughput

0.479

High

160152

LATS1
Serine/threonine-protein kinase LATS1

1

2

High-throughput

0.479

High

160153

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.479

High

160155

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

9

High-throughput

0.479

High

160156

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

160157

MYCN
N-myc proto-oncogene protein

1

20

High-throughput

0.479

High

160159

HS90B
Heat shock protein HSP 90-beta

1

6

High-throughput

0.479

High

160160

BCR
Breakpoint cluster region protein

1

2

High-throughput

0.479

High

160162

PHB1
Prohibitin 1

1

7

High-throughput

0.479

High

160164

MDHM
Malate dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

160165

NKX21
Homeobox protein Nkx-2.1

1

17

High-throughput

0.479

High

160166

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

13

High-throughput

0.479

High

160168

MECP2
Methyl-CpG-binding protein 2

1

19

High-throughput

0.479

High

160169

HDGF
Hepatoma-derived growth factor

1

18

High-throughput

0.479

High

160173

RNF4
E3 ubiquitin-protein ligase RNF4

1

5

High-throughput

0.479

High

160176

VIGLN
Vigilin

1

17

High-throughput

0.479

High

160179

TADBP
TAR DNA-binding protein 43

1

16

Small-scale

0.479

High

160183

SUZ12
Polycomb protein SUZ12

1

8

High-throughput

0.479

High

160184

EZH2
Histone-lysine N-methyltransferase EZH2

1

20

High-throughput

0.479

High

160185

LARP7
La-related protein 7

1

20

High-throughput

0.479

High

160193

CGAS
Cyclic GMP-AMP synthase

1

7

High-throughput

0.479

High

160194

FBX22
F-box only protein 22

1

2

High-throughput

0.479

High

160198

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

160208

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

11

High-throughput

0.479

High

160210

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

160213

TR150
Thyroid hormone receptor-associated protein 3

1

14

High-throughput

0.479

High

160189

SHLD2
Shieldin complex subunit 2

1

0

High-throughput

0.458

High

160177

FMR1
Fragile X messenger ribonucleoprotein 1

1

14

High-throughput

0.457

High

160172

SUMO1
Small ubiquitin-related modifier 1

1

10

Small-scale

0.445

High

160199

FGF11
Fibroblast growth factor 11

1

5

High-throughput

0.445

High

160203

PARK7
Parkinson disease protein 7

1

1

Small-scale

0.445

High

132802

ODPX
Pyruvate dehydrogenase protein X component, mitochondrial

1

5

High-throughput

0.437

High

160163

BASI
Basigin

1

1

High-throughput

0.437

High

160206

PKHA4
Pleckstrin homology domain-containing family A member 4

1

12

High-throughput

0.437

High

160201

CI072
Guanine nucleotide exchange factor C9orf72

1

0

Small-scale

0.426

High

160212

ABT1
Activator of basal transcription 1

1

0

High-throughput

0.426

High

160195

LNX1
E3 ubiquitin-protein ligase LNX

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025