HitPredict

Interactor 1: AURKA (O14965)
Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (Breast tumor-amplified kinase) (Ipl1- and aurora-related kinase 1) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase Ayk1) (Serine/threonine-protein kinase aurora-A)
Gene: AURKA

Interactor 2: DYL1 (P63167)
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN)
Gene: DYNLL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32989298
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000776 - kinetochore GO:0005634 - nucleus GO:0005813 - centrosome GO:0005829 - cytosol GO:0006915 - apoptotic process and 1 others more... GO:0072686 - mitotic spindle
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 403 Hs			1 89
+	Hs
		568621 KAPCA_HUMAN (117-400): 5.82e-136: 394: 29.76		DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00
+	Hs
		610709 KAPCB_HUMAN (117-400): 2.4e-135: 393: 30.80		DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00
+	Hs
		568762 KAPCA_HUMAN (117-400): 5.82e-136: 394: 29.76		DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26
+	Hs
		610764 KAPCB_HUMAN (117-400): 2.4e-135: 393: 30.80		DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26