Interactor 1: AURKA (O14965)
Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (Breast tumor-amplified kinase) (Ipl1- and aurora-related kinase 1) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase Ayk1) (Serine/threonine-protein kinase aurora-A)
Gene: AURKA

Interactor 2: TYY1 (P25490)
Transcriptional repressor protein YY1 (Delta transcription factor) (INO80 complex subunit S) (NF-E1) (Yin and yang 1) (YY-1)
Gene: YY1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 28218735
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~zf-C2H2
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0010629 - negative regulation of gene expression
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 403
Hs

1 414
+ Hs
+ Hs
+ Zm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024