Interactor 1: MYPT1 (O14974)
Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit)
Gene: PPP1R12A

Interactor 2: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 25144556
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~P53
Common GO terms GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005829 - cytosol
and 3 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 1030
Hs

1 393
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024