HitPredict

Interactor 1: APAF (O14727)
Apoptotic protease-activating factor 1 (APAF-1)
Gene: APAF1

Interactor 2: DEFI8 (Q6ZN54)
Differentially expressed in FDCP 8 homolog (DEF-8)
Gene: DEF8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1248 Hs			1 512
+	Hs
		603350 TEP1_HUMAN (539-1073): 4e-57: 220: 13.77		KPCA_HUMAN (151-250): 2.81e-20: 96.3: 16.83
+	Hs
		992693 RACK1_HUMAN (964-1207): 2.1e-10: 65.5: 25.29		KPCE_HUMAN (151-250): 8.1e-23: 104: 17.43
+	Hs
		436648 RACK1_HUMAN (964-1207): 2.1e-10: 65.5: 25.29		KPCB_HUMAN (151-269): 6.32e-21: 98.3: 15.00
+	Mm
		996060 RACK1_MOUSE (964-1207): 2.1e-10: 65.5: 25.29		KPCB_MOUSE (151-269): 5.88e-21: 98.3: 15.00
+	Hs
		603229 RACK1_HUMAN (964-1207): 2.1e-10: 65.5: 25.29		KPCA_HUMAN (151-250): 2.81e-20: 96.3: 16.83