HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: CCND1 (P24385)
G1/S-specific cyclin-D1 (B-cell lymphoma 1 protein) (BCL-1) (BCL-1 oncogene) (PRAD1 oncogene)
Gene: CCND1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	21654808, 12529437
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031965 - nuclear membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1071 Hs			1 295
+	Hs
		162379 XPO1_HUMAN (1-1071): 0: 1022: 100.00		CCNB1_HUMAN (5-282): 3.94e-89: 273: 20.64
+	Hs
		162288 XPO1_HUMAN (1-1071): 0: 1022: 100.00		CCNB2_HUMAN (7-287): 1.34e-85: 263: 18.09
+	Xl
		526767 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		CCNB2_XENLA (7-287): 9.68e-87: 266: 17.38
+	Hs
		943805 XPO5_HUMAN (26-665): 5.8e-100: 344: 16.12		CCNA1_HUMAN (7-281): 7.64e-89: 274: 23.91
+	Hs
		538547 IMB1_HUMAN (27-908): 2.89e-90: 311: 11.32		CCNB1_HUMAN (5-282): 3.94e-89: 273: 20.64
+	Hs
		622533 XPO5_HUMAN (26-665): 5.8e-100: 344: 16.12		CCND1_HUMAN (1-295): 1.33e-74: 232: 100.00
+	Dm
		540504 Q9VQG0_DROME (24-1023): 1.78e-89: 309: 12.89		CCNA_DROME (11-286): 1.1e-74: 238: 23.83
+	Hs
		624593 IMB1_HUMAN (27-908): 2.89e-90: 311: 11.32		CCNE1_HUMAN (25-208): 7.3e-18: 84.7: 28.50