Protein: CARM1
Histone-arginine methyltransferase CARM1 (EC 2.1.1.319) (Coactivator-associated arginine methyltransferase 1) (Protein arginine N-methyltransferase 4)

Gene: CARM1
Organism: Homo sapiens
Interactions: 208
UniProt ID: Q86X55

Gene Ontology (top 5):
GO:0000976 - transcription cis-regulatory region binding
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1067481

EP300
Histone acetyltransferase p300

8

7

Small-scale

0.754

High

1293443

NCOA3
Nuclear receptor coactivator 3

6

8

Small-scale

0.738

High

998500

H31
Histone H3.1

6

16

Small-scale

0.729

High

1293383

CBP
CREB-binding protein

4

5

Small-scale

0.704

High

1045469

TF65
Transcription factor p65

4

3

Small-scale

0.698

High

1293438

GRIP1
Glutamate receptor-interacting protein 1

3

2

Small-scale

0.650

High

1293386

SMRC1
SWI/SNF complex subunit SMARCC1

2

3

Small-scale

0.649

High

1293365

CARM1
Histone-arginine methyltransferase CARM1

1

16

Small-scale

0.647

High

1293422

ANM8
Protein arginine N-methyltransferase 8

1

16

Small-scale

0.647

High

372470

MYC
Myc proto-oncogene protein

3

10

Small-scale

0.640

High

1293391

P33MX
Putative monooxygenase p33MONOX

3

0

High-throughput

0.638

High

1293433

IL36A
Interleukin-36 alpha

3

0

High-throughput

0.638

High

1293367

TCAM1
TIR domain-containing adapter molecule 1

3

0

High-throughput

0.634

High

185826

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

2

7

High-throughput

0.628

High

897329

CDK7
Cyclin-dependent kinase 7

2

2

High-throughput

0.628

High

914031

RIDA
2-iminobutanoate/2-iminopropanoate deaminase

2

1

High-throughput

0.628

High

1293399

KI16B
Kinesin-like protein KIF16B

2

1

High-throughput

0.628

High

1293408

RBM4
RNA-binding protein 4

2

7

High-throughput

0.628

High

1293366

DZIP3
E3 ubiquitin-protein ligase DZIP3

2

4

Small-scale

0.624

High

1293404

ANM1
Protein arginine N-methyltransferase 1

1

16

High-throughput

0.618

High

584115

FOSL2
Fos-related antigen 2

2

3

High-throughput

0.611

High

1112583

CUL1
Cullin-1

2

10

Small-scale

0.611

High

1113594

CUL3
Cullin-3

2

10

High-throughput

0.611

High

1293385

CSN5
COP9 signalosome complex subunit 5

2

7

High-throughput

0.611

High

1150395

NCOA2
Nuclear receptor coactivator 2

2

8

Small-scale

0.602

High

1153770

NCOA1
Nuclear receptor coactivator 1

2

8

Small-scale

0.602

High

1272909

3BP5L
SH3 domain-binding protein 5-like

2

0

High-throughput

0.602

High

1293381

PRCC
Proline-rich protein PRCC

2

0

High-throughput

0.602

High

910973

IMA1
Importin subunit alpha-1

2

2

High-throughput

0.601

High

1148305

CNN3
Calponin-3

2

1

High-throughput

0.601

High

903407

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

4

Small-scale

0.597

High

402626

ALDOA
Fructose-bisphosphate aldolase A

2

0

High-throughput

0.595

High

1293418

JUPI2
Jupiter microtubule associated homolog 2

2

0

High-throughput

0.595

High

414139

P53
Cellular tumor antigen p53

2

6

Small-scale

0.595

High

606893

CEBPB
CCAAT/enhancer-binding protein beta

1

3

Small-scale

0.589

High

1293429

HEY2
Hairy/enhancer-of-split related with YRPW motif protein 2

2

0

High-throughput

0.585

High

242180

PRKN
E3 ubiquitin-protein ligase parkin

2

7

High-throughput

0.584

High

1100084

TIF1B
Transcription intermediary factor 1-beta

2

8

Small-scale

0.584

High

246725

KDM1A
Lysine-specific histone demethylase 1A

1

4

Small-scale

0.578

High

1293427

GTSE1
G2 and S phase-expressed protein 1

2

0

High-throughput

0.576

High

1293395

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

3

High-throughput

0.573

High

1293401

QKI
KH domain-containing RNA-binding protein QKI

1

7

High-throughput

0.573

High

631322

RAB5A
Ras-related protein Rab-5A

2

3

High-throughput

0.571

High

370717

FOS
Protein c-Fos

1

7

Small-scale

0.561

High

838373

STA5A
Signal transducer and activator of transcription 5A

1

4

Small-scale

0.561

High

1093265

FLII
Protein flightless-1 homolog

1

2

Small-scale

0.561

High

228307

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.549

High

955885

GMFB
Glia maturation factor beta

2

1

High-throughput

0.549

High

154715

ARI1A
AT-rich interactive domain-containing protein 1A

1

3

Small-scale

0.536

High

401086

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

6

High-throughput

0.536

High

517482

GLI2
Zinc finger protein GLI2

1

6

High-throughput

0.536

High

606133

DESM
Desmin

1

9

High-throughput

0.536

High

843729

HD
Huntingtin

1

2

High-throughput

0.536

High

889764

CLK3
Dual specificity protein kinase CLK3

1

6

High-throughput

0.536

High

939205

SUMO3
Small ubiquitin-related modifier 3

1

4

High-throughput

0.536

High

944154

WDR4
tRNA

1

8

High-throughput

0.536

High

952936

ACTB
Actin, cytoplasmic 1

1

3

Small-scale

0.536

High

1029109

E2F1
Transcription factor E2F1

1

4

Small-scale

0.536

High

1109558

4EBP1
Eukaryotic translation initiation factor 4E-binding protein 1

1

1

High-throughput

0.536

High

1110372

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

1

1

High-throughput

0.536

High

1112904

CUL2
Cullin-2

1

10

High-throughput

0.536

High

1158797

KCC4
Calcium/calmodulin-dependent protein kinase type IV

1

1

High-throughput

0.536

High

1291042

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

4

High-throughput

0.536

High

1293368

NUDC3
NudC domain-containing protein 3

1

2

High-throughput

0.536

High

1293371

ARFG1
ADP-ribosylation factor GTPase-activating protein 1

1

3

High-throughput

0.536

High

1293377

SMRC2
SWI/SNF complex subunit SMARCC2

1

6

Small-scale

0.536

High

1293378

RIN3
Ras and Rab interactor 3

1

4

High-throughput

0.536

High

1293379

PDC6I
Programmed cell death 6-interacting protein

1

8

High-throughput

0.536

High

1293380

ATG4A
Cysteine protease ATG4A

1

1

High-throughput

0.536

High

1293387

CUL5
Cullin-5

1

10

High-throughput

0.536

High

1293388

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

1

1

Small-scale

0.536

High

1293397

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

1

Small-scale

0.536

High

1293398

SCYL1
N-terminal kinase-like protein

1

1

High-throughput

0.536

High

1293406

DPYL5
Dihydropyrimidinase-related protein 5

1

2

High-throughput

0.536

High

1293413

IQCN
IQ domain-containing protein N

1

1

High-throughput

0.536

High

1293415

P63
Tumor protein 63

1

6

Small-scale

0.536

High

1293417

EGLN3
Prolyl hydroxylase EGLN3

1

3

High-throughput

0.536

High

1293442

M4K5
Mitogen-activated protein kinase kinase kinase kinase 5

1

3

High-throughput

0.536

High

1253848

SRCAP
Helicase SRCAP

1

7

Small-scale

0.527

High

831010

CCNF
Cyclin-F

1

4

High-throughput

0.515

High

846919

ETV4
ETS translocation variant 4

1

3

High-throughput

0.515

High

873978

NRIP1
Nuclear receptor-interacting protein 1

1

1

Small-scale

0.515

High

1293440

C170B
Centrosomal protein of 170 kDa protein B

1

2

High-throughput

0.515

High

276841

VATG1
V-type proton ATPase subunit G 1

1

0

High-throughput

0.513

High

469741

GSTA1
Glutathione S-transferase A1

1

0

High-throughput

0.513

High

608300

EGLN
Endoglin

1

0

High-throughput

0.513

High

880455

RPIA
Ribose-5-phosphate isomerase

1

0

High-throughput

0.513

High

916176

BIEA
Biliverdin reductase A

1

0

High-throughput

0.513

High

976383

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.513

High

1145818

IRF4
Interferon regulatory factor 4

1

0

High-throughput

0.513

High

1244456

DCNL2
DCN1-like protein 2

1

0

High-throughput

0.513

High

1293370

ZGPAT
Zinc finger CCCH-type with G patch domain-containing protein

1

0

High-throughput

0.513

High

1293375

CDC26
Anaphase-promoting complex subunit CDC26

1

0

High-throughput

0.513

High

1293376

MPLKI
M-phase-specific PLK1-interacting protein

1

0

High-throughput

0.513

High

1293382

THRSP
Thyroid hormone-inducible hepatic protein

1

0

High-throughput

0.513

High

1293393

ESS2
Splicing factor ESS-2 homolog

1

0

High-throughput

0.513

High

1293403

PCY2
Ethanolamine-phosphate cytidylyltransferase

1

0

High-throughput

0.513

High

1293407

LRC61
Leucine-rich repeat-containing protein 61

1

0

High-throughput

0.513

High

1293409

RTF2
Replication termination factor 2

1

0

High-throughput

0.513

High

1293420

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.513

High

1293426

MED9
Mediator of RNA polymerase II transcription subunit 9

1

0

High-throughput

0.513

High

993640

UBC9
SUMO-conjugating enzyme UBC9

1

2

High-throughput

0.508

High

1293405

SPAG8
Sperm-associated antigen 8

1

3

High-throughput

0.508

High

1293430

MALT1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1

1

1

High-throughput

0.508

High

1293431

DAXX
Death domain-associated protein 6

1

1

High-throughput

0.508

High

1293439

PYGO1
Pygopus homolog 1

1

5

High-throughput

0.508

High

181136

AXIN1
Axin-1

1

4

Small-scale

0.501

High

581686

MYOD1
Myoblast determination protein 1

1

4

Small-scale

0.501

High

581774

MYOG
Myogenin

1

4

Small-scale

0.501

High

764874

CTNB1
Catenin beta-1

1

5

Small-scale

0.501

High

1132661

MEF2D
Myocyte-specific enhancer factor 2D

1

2

Small-scale

0.501

High

1287803

PABP2
Polyadenylate-binding protein 2

1

18

Small-scale

0.501

High

275184

GGCT
Gamma-glutamylcyclotransferase

1

0

High-throughput

0.493

High

155205

NCKP5
Nck-associated protein 5

1

6

High-throughput

0.489

High

771788

SCN4A
Sodium channel protein type 4 subunit alpha

1

2

High-throughput

0.489

High

1232089

VASN
Vasorin

1

2

High-throughput

0.489

High

1293392

RB39B
Ras-related protein Rab-39B

1

1

High-throughput

0.489

High

1293419

LN28A
Protein lin-28 homolog A

1

6

High-throughput

0.484

High

1239619

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

1

0

Small-scale

0.479

High

125521

LEG9
Galectin-9

1

2

High-throughput

0.479

High

162621

ANM5
Protein arginine N-methyltransferase 5

1

16

Small-scale

0.479

High

260142

BRD4
Bromodomain-containing protein 4

1

4

High-throughput

0.479

High

262401

DTNB
Dystrobrevin beta

1

5

High-throughput

0.479

High

315749

RECQ4
ATP-dependent DNA helicase Q4

1

10

High-throughput

0.479

High

385920

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

6

High-throughput

0.479

High

396445

ESR1
Estrogen receptor

1

14

Small-scale

0.479

High

406352

MYCN
N-myc proto-oncogene protein

1

10

High-throughput

0.479

High

485243

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

20

Small-scale

0.479

High

487491

PARP1
Poly [ADP-ribose] polymerase 1

1

4

Small-scale

0.479

High

589076

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.479

High

593151

CREB1
Cyclic AMP-responsive element-binding protein 1

1

1

Small-scale

0.479

High

695862

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.479

High

711719

RABP2
Cellular retinoic acid-binding protein 2

1

1

High-throughput

0.479

High

731436

STIP1
Stress-induced-phosphoprotein 1

1

8

High-throughput

0.479

High

768576

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.479

High

771006

RORA
Nuclear receptor ROR-alpha

1

18

Small-scale

0.479

High

799265

BRCA1
Breast cancer type 1 susceptibility protein

1

8

High-throughput

0.479

High

862672

UTRN
Utrophin

1

9

High-throughput

0.479

High

879243

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

12

High-throughput

0.479

High

912511

MP2K6
Dual specificity mitogen-activated protein kinase kinase 6

1

5

High-throughput

0.479

High

965074

WDR5
WD repeat-containing protein 5

1

7

Small-scale

0.479

High

965762

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

14

Small-scale

0.479

High

970729

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.479

High

992243

SKP1
S-phase kinase-associated protein 1

1

3

Small-scale

0.479

High

1016996

H33
Histone H3.3

1

16

Small-scale

0.479

High

1050808

PTN12
Tyrosine-protein phosphatase non-receptor type 12

1

1

High-throughput

0.479

High

1088900

TP53B
TP53-binding protein 1

1

1

High-throughput

0.479

High

1104843

SNTB2
Beta-2-syntrophin

1

1

High-throughput

0.479

High

1107881

SQSTM
Sequestosome-1

1

1

High-throughput

0.479

High

1118440

SNTB1
Beta-1-syntrophin

1

3

High-throughput

0.479

High

1120233

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

20

Small-scale

0.479

High

1138368

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

4

High-throughput

0.479

High

1140506

KIF14
Kinesin-like protein KIF14

1

3

High-throughput

0.479

High

1149922

TERF2
Telomeric repeat-binding factor 2

1

4

High-throughput

0.479

High

1161524

IF16
Gamma-interferon-inducible protein 16

1

4

High-throughput

0.479

High

1219797

MT21C
Protein-lysine methyltransferase METTL21C

1

13

High-throughput

0.479

High

1220619

RN123
E3 ubiquitin-protein ligase RNF123

1

13

High-throughput

0.479

High

1254483

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.479

High

1260600

ASXL2
Putative Polycomb group protein ASXL2

1

7

High-throughput

0.479

High

1293369

ASXL1
Polycomb group protein ASXL1

1

5

High-throughput

0.479

High

1293373

MTMRE
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR14

1

1

High-throughput

0.479

High

1293384

KAT2B
Histone acetyltransferase KAT2B

1

4

Small-scale

0.479

High

1293389

FBXW7
F-box/WD repeat-containing protein 7

1

6

High-throughput

0.479

High

1293390

FBX32
F-box only protein 32

1

1

High-throughput

0.479

High

1293394

MTMR8
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR8

1

1

High-throughput

0.479

High

1293400

CI072
Guanine nucleotide exchange factor C9orf72

1

2

High-throughput

0.479

High

1293402

NR1H4
Bile acid receptor

1

20

Small-scale

0.479

High

1293416

PKHA4
Pleckstrin homology domain-containing family A member 4

1

9

High-throughput

0.479

High

1293421

MLXPL
Carbohydrate-responsive element-binding protein

1

5

Small-scale

0.479

High

1293423

RNC
Ribonuclease 3

1

4

High-throughput

0.479

High

1293432

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

1293435

TNR6B
Trinucleotide repeat-containing gene 6B protein

1

1

High-throughput

0.479

High

1293436

MTMR6
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR6

1

1

High-throughput

0.479

High

1293441

DTNA
Dystrobrevin alpha

1

5

High-throughput

0.479

High

657623

GCSP
Glycine dehydrogenase

1

0

High-throughput

0.458

High

898494

PPT1
Palmitoyl-protein thioesterase 1

1

0

High-throughput

0.458

High

1135727

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.458

High

1293372

KDF1
Keratinocyte differentiation factor 1

1

0

High-throughput

0.458

High

1293434

FBX9
F-box only protein 9

1

0

Small-scale

0.458

High

1293437

UB2D4
Ubiquitin-conjugating enzyme E2 D4

1

1

High-throughput

0.457

High

520601

RARA
Retinoic acid receptor alpha

1

18

Small-scale

0.445

High

530038

TAU
Microtubule-associated protein tau

1

7

High-throughput

0.445

High

626275

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

6

Small-scale

0.445

High

720777

PUR8
Adenylosuccinate lyase

1

1

High-throughput

0.445

High

934818

TERA
Transitional endoplasmic reticulum ATPase

1

4

High-throughput

0.445

High

952232

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

5

High-throughput

0.445

High

1086625

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

1

Small-scale

0.445

High

1209345

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

5

High-throughput

0.445

High

1226155

CP135
Centrosomal protein of 135 kDa

1

6

High-throughput

0.445

High

1293412

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

5

High-throughput

0.445

High

1293414

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

5

High-throughput

0.445

High

412203

NTRK1
High affinity nerve growth factor receptor

1

3

High-throughput

0.437

High

642957

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

1

High-throughput

0.437

High

908280

AFF1
AF4/FMR2 family member 1

1

3

Small-scale

0.437

High

1228987

RNF43
E3 ubiquitin-protein ligase RNF43

1

1

High-throughput

0.437

High

1290248

MGDP1
Magnesium-dependent phosphatase 1

1

1

High-throughput

0.437

High

1293410

ACE2
Angiotensin-converting enzyme 2

1

2

High-throughput

0.437

High

1293411

ASXL3
Putative Polycomb group protein ASXL3

1

10

High-throughput

0.437

High

1293424

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

3

High-throughput

0.437

High

1288890

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

0

High-throughput

0.426

High

1293396

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.426

High

1293374

MOT11
Monocarboxylate transporter 11

1

1

High-throughput

0.407

High

1293428

USE1
Vesicle transport protein USE1

1

1

Small-scale

0.407

High

211207

CMIP4
Ciliary microtubule inner protein 4

3

0

High-throughput

0.347

High

1293425

NECP2
Adaptin ear-binding coat-associated protein 2

3

0

High-throughput

0.347

High

573299

ACYP2
Acylphosphatase-2

1

0

High-throughput

0.279

Low

1241214

CA094
Uncharacterized protein C1orf94

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025