Protein: ANM2
Protein arginine N-methyltransferase 2 (EC 2.1.1.319) (Histone-arginine N-methyltransferase PRMT2)

Gene: ANM2, PRMT2
Organism: Homo sapiens
Interactions: 99
UniProt ID: P55345

Gene Ontology (top 5):
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

938132

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

4

3

High-throughput

0.905

High

507130

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

3

6

High-throughput

0.861

High

938116

KSR1
Kinase suppressor of Ras 1

3

4

High-throughput

0.861

High

938107

KANK2
KN motif and ankyrin repeat domain-containing protein 2

3

3

High-throughput

0.839

High

856610

BAG6
Large proline-rich protein BAG6

2

4

High-throughput

0.767

High

938149

SHAN1
SH3 and multiple ankyrin repeat domains protein 1

1

2

High-throughput

0.698

High

843423

HD
Huntingtin

4

2

High-throughput

0.692

High

72928

ESPN
Espin

1

1

High-throughput

0.691

High

136349

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

6

High-throughput

0.691

High

938110

SAMD1
Sterile alpha motif domain-containing protein 1

4

4

High-throughput

0.691

High

938125

P121A
Nuclear envelope pore membrane protein POM 121

4

5

High-throughput

0.691

High

938150

FHOD1
FH1/FH2 domain-containing protein 1

4

2

High-throughput

0.691

High

175864

SET1A
Histone-lysine N-methyltransferase SETD1A

3

5

High-throughput

0.667

High

896360

ERF
ETS domain-containing transcription factor ERF

3

3

High-throughput

0.667

High

938104

TIGD5
Tigger transposable element-derived protein 5

3

2

High-throughput

0.667

High

938112

CO039
Uncharacterized protein C15orf39

3

2

High-throughput

0.667

High

938119

PPM1E
Protein phosphatase 1E

3

1

High-throughput

0.667

High

938123

TTC28
Tetratricopeptide repeat protein 28

3

6

High-throughput

0.667

High

938128

LMBL3
Lethal(3)malignant brain tumor-like protein 3

3

2

High-throughput

0.667

High

938134

SETD5
Histone-lysine N-methyltransferase SETD5

3

2

High-throughput

0.667

High

938145

SET1B
Histone-lysine N-methyltransferase SETD1B

3

5

High-throughput

0.667

High

869470

TNFL6
Tumor necrosis factor ligand superfamily member 6

4

0

High-throughput

0.661

High

395765

ESR1
Estrogen receptor

2

14

Small-scale

0.656

High

214404

RIPK2
Receptor-interacting serine/threonine-protein kinase 2

1

1

High-throughput

0.656

High

938137

ANM8
Protein arginine N-methyltransferase 8

1

17

Small-scale

0.647

High

938127

VCIP1
Deubiquitinating protein VCPIP1

3

0

High-throughput

0.638

High

938140

CXXC1
CXXC-type zinc finger protein 1

3

0

High-throughput

0.638

High

938131

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

2

13

Small-scale

0.636

High

938109

PSRC1
Proline/serine-rich coiled-coil protein 1

3

0

High-throughput

0.634

High

938111

FIP1
Pre-mRNA 3'-end-processing factor FIP1

2

2

High-throughput

0.620

High

213877

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

1

High-throughput

0.618

High

241215

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.618

High

699665

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

6

High-throughput

0.618

High

938091

ANM2
Protein arginine N-methyltransferase 2

1

16

Small-scale

0.618

High

176044

KDM6B
Lysine-specific demethylase 6B

2

1

Small-scale

0.614

High

515685

TPC2B
Trafficking protein particle complex subunit 2B

3

0

High-throughput

0.613

High

938148

SALL2
Sal-like protein 2

2

1

High-throughput

0.611

High

938141

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

3

1

High-throughput

0.609

High

442651

RB
Retinoblastoma-associated protein

1

2

Small-scale

0.578

High

938102

SF01
Splicing factor 1

2

7

High-throughput

0.576

High

938098

KANK1
KN motif and ankyrin repeat domain-containing protein 1

1

3

High-throughput

0.575

High

938114

GET4
Golgi to ER traffic protein 4 homolog

2

0

High-throughput

0.547

High

354934

CHK2
Serine/threonine-protein kinase Chk2

1

3

High-throughput

0.541

High

688225

TTP
mRNA decay activator protein ZFP36

1

2

High-throughput

0.541

High

887504

PSB3
Proteasome subunit beta type-3

1

1

High-throughput

0.541

High

888588

YLPM1
YLP motif-containing protein 1

1

5

High-throughput

0.541

High

938095

CBLB
E3 ubiquitin-protein ligase CBL-B

1

2

High-throughput

0.541

High

938105

IQEC2
IQ motif and SEC7 domain-containing protein 2

1

6

High-throughput

0.541

High

938117

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

8

High-throughput

0.541

High

938124

DAZP1
DAZ-associated protein 1

1

19

High-throughput

0.541

High

938138

RBM12
RNA-binding protein 12

1

17

High-throughput

0.541

High

938139

RBM22
Pre-mRNA-splicing factor RBM22

1

6

High-throughput

0.541

High

938144

MYO6
Unconventional myosin-VI

1

2

High-throughput

0.541

High

938147

WBP11
WW domain-binding protein 11

1

2

High-throughput

0.541

High

325758

UBR5
E3 ubiquitin-protein ligase UBR5

1

9

High-throughput

0.536

High

938113

UBP51
Ubiquitin carboxyl-terminal hydrolase 51

1

1

High-throughput

0.536

High

938136

PRD11
PR domain-containing protein 11

1

3

High-throughput

0.536

High

49299

SHOT1
Shootin-1

1

0

High-throughput

0.518

High

67467

ZSWM8
Zinc finger SWIM domain-containing protein 8

1

0

High-throughput

0.518

High

938093

E2F1
Transcription factor E2F1

1

4

Small-scale

0.515

High

938143

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.513

High

875599

PRC2A
Protein PRRC2A

1

7

Small-scale

0.508

High

938130

SPAG8
Sperm-associated antigen 8

1

3

High-throughput

0.508

High

485015

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

20

Small-scale

0.501

High

938100

R3HD1
R3H domain-containing protein 1

1

2

High-throughput

0.494

High

938151

CXA3
Gap junction alpha-3 protein

1

1

High-throughput

0.489

High

133647

WASL
Actin nucleation-promoting factor WASL

1

2

High-throughput

0.481

High

442906

PRGR
Progesterone receptor

1

13

Small-scale

0.479

High

446806

NPM
Nucleophosmin

1

1

Small-scale

0.479

High

533331

THB
Thyroid hormone receptor beta

1

18

Small-scale

0.479

High

580390

ALDR
Aldo-keto reductase family 1 member B1

1

1

Small-scale

0.479

High

622786

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

1

6

High-throughput

0.479

High

625790

RXRA
Retinoic acid receptor RXR-alpha

1

10

Small-scale

0.479

High

938092

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

14

Small-scale

0.479

High

938094

PPARA
Peroxisome proliferator-activated receptor alpha

1

20

Small-scale

0.479

High

938099

NCOA6
Nuclear receptor coactivator 6

1

6

Small-scale

0.479

High

938103

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

3

High-throughput

0.479

High

938120

ESR2
Estrogen receptor beta

1

12

Small-scale

0.479

High

938129

DMRTB
Doublesex- and mab-3-related transcription factor B1

1

0

High-throughput

0.460

High

938133

ZN341
Zinc finger protein 341

1

0

High-throughput

0.460

High

744648

TF2H1
General transcription factor IIH subunit 1

1

0

High-throughput

0.458

High

770362

T2FA
General transcription factor IIF subunit 1

1

0

High-throughput

0.458

High

938096

TF2H2
General transcription factor IIH subunit 2

1

0

High-throughput

0.458

High

938097

TF2H3
General transcription factor IIH subunit 3

1

0

High-throughput

0.458

High

938121

TF2H4
General transcription factor IIH subunit 4

1

0

High-throughput

0.458

High

938122

RBPMS
RNA-binding protein with multiple splicing

1

0

High-throughput

0.458

High

258552

DIAP2
Protein diaphanous homolog 2

1

2

High-throughput

0.445

High

288914

ERAL1
GTPase Era, mitochondrial

1

3

High-throughput

0.445

High

938108

IQEC1
IQ motif and SEC7 domain-containing protein 1

1

6

High-throughput

0.445

High

938101

MTFR1
Mitochondrial fission regulator 1

1

0

High-throughput

0.426

High

938106

CHCH9
Putative coiled-coil-helix-coiled-coil-helix domain-containing protein CHCHD2P9, mitochondrial

1

0

High-throughput

0.426

High

938126

PRR11
Proline-rich protein 11

1

0

High-throughput

0.426

High

938142

CEIP2
Cell surface hyaluronidase CEMIP2

1

0

High-throughput

0.426

High

938146

MYRF
Myelin regulatory factor

1

0

High-throughput

0.426

High

938135

ANTR1
Anthrax toxin receptor 1

4

0

High-throughput

0.360

High

63752

KRBA1
Protein KRBA1

3

0

High-throughput

0.347

High

938115

PKHH3
Pleckstrin homology domain-containing family H member 3

2

0

High-throughput

0.298

High

938118

SCRB1
Scavenger receptor class B member 1

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025