HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: IKBA (P25963)
NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkB-alpha) (IkappaBalpha) (Major histocompatibility complex enhancer-binding protein MAD3)
Gene: NFKBIA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26673895
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1071 Hs			1 317
+	Hs
		121547 XPO1_HUMAN (1-1071): 0: 1022: 100.00		IKBE_HUMAN (3-315): 1.28e-74: 239: 32.10
+	Xl
		1117304 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q4KLR5_XENLA (6-315): 2.23e-77: 241: 32.29
+	Hs
		162635 XPO1_HUMAN (1-1071): 0: 1022: 100.00		NFKB2_HUMAN (68-294): 6.66e-64: 218: 34.32
+	Xl
		1150110 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q6DCW3_XENLA (12-315): 5.58e-70: 221: 59.61
+	Hs
		163272 XPO1_HUMAN (1-1071): 0: 1022: 100.00		Q9H4D1_HUMAN (136-316): 1.24e-33: 132: 24.31
+	Hs
		162298 XPO1_HUMAN (1-1071): 0: 1022: 100.00		TNKS1_HUMAN (187-313): 1.98e-30: 123: 18.75
+	Hs
		163311 XPO1_HUMAN (1-1071): 0: 1022: 100.00		TANC2_HUMAN (3-181): 3.02e-21: 96.6: 17.88
+	Hs
		162399 XPO1_HUMAN (1-1071): 0: 1022: 100.00		NFKB1_HUMAN (31-196): 3.47e-20: 93.1: 23.35
+	Xl
		251120 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		NFKB2_XENLA (52-209): 2.49e-23: 102: 25.00
+	Hs
		162776 XPO1_HUMAN (1-1071): 0: 1022: 100.00		IKBB_HUMAN (68-169): 5.17e-13: 70.8: 28.16
+	Hs
		163457 XPO1_HUMAN (1-1071): 0: 1022: 100.00		ANR50_HUMAN (2-66): 2.02e-09: 60.6: 4.62
+	Mm
		1119759 XPO7_MOUSE (23-1013): 5.43e-120: 397: 13.01		ANR28_MOUSE (3-271): 1.83e-49: 178: 19.86
+	Hs
		155558 TNPO2_HUMAN (33-1045): 7.78e-129: 415: 14.41		RIPK4_HUMAN (136-316): 6.43e-34: 133: 24.31
+	Hs
		155639 TNPO2_HUMAN (33-1045): 7.78e-129: 415: 14.41		Q9H4D1_HUMAN (136-316): 1.24e-33: 132: 24.31
+	Hs
		207918 XPOT_HUMAN (29-1023): 3.55e-126: 410: 14.85		RIPK4_HUMAN (136-316): 6.43e-34: 133: 24.31
+	Mm
		71300 XPO7_MOUSE (23-1013): 5.43e-120: 397: 13.01		ANR44_MOUSE (91-266): 7.41e-10: 62: 30.22
+	Hs
		1206059 XPO5_HUMAN (26-665): 5.8e-100: 344: 16.12		MIB1_HUMAN (187-313): 7.22e-23: 101: 18.11