Protein: ZKSC4
Zinc finger protein with KRAB and SCAN domains 4 (P373c6.1) (Zinc finger protein 307) (Zinc finger protein 427)

Gene: ZKSC4, ZKSCAN4
Organism: Homo sapiens
Interactions: 104
UniProt ID: Q969J2

Gene Ontology (top 5):
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005654 - nucleoplasm
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1380362

ZSC32
Zinc finger and SCAN domain-containing protein 32

7

19

High-throughput

0.967

High

600353

ZNF24
Zinc finger protein 24

7

20

High-throughput

0.959

High

1380361

ZN446
Zinc finger protein 446

5

19

High-throughput

0.933

High

1380349

ZN496
Zinc finger protein 496

5

19

High-throughput

0.932

High

1380364

ZKSC7
Zinc finger protein with KRAB and SCAN domains 7

5

19

High-throughput

0.932

High

1338602

ZN397
Zinc finger protein 397

4

20

High-throughput

0.905

High

1380375

ZSC21
Zinc finger and SCAN domain-containing protein 21

4

19

High-throughput

0.902

High

600562

ZSC20
Zinc finger and SCAN domain-containing protein 20

4

18

High-throughput

0.897

High

1380350

PGBD1
PiggyBac transposable element-derived protein 1

3

20

High-throughput

0.875

High

1353488

ZN483
Zinc finger protein 483

3

20

High-throughput

0.863

High

1380346

ZKSC4
Zinc finger protein with KRAB and SCAN domains 4

3

19

High-throughput

0.862

High

1322337

ZN444
Zinc finger protein 444

3

20

High-throughput

0.861

High

1380351

ZN396
Zinc finger protein 396

3

20

High-throughput

0.861

High

600434

ZKSC1
Zinc finger protein with KRAB and SCAN domains 1

3

19

High-throughput

0.855

High

1380354

ZKSC3
Zinc finger protein with KRAB and SCAN domains 3

3

19

High-throughput

0.855

High

944202

SCND1
SCAN domain-containing protein 1

6

20

High-throughput

0.852

High

163510

ZN213
Zinc finger protein 213

2

20

High-throughput

0.811

High

1152378

ZN174
Zinc finger protein 174

2

20

High-throughput

0.811

High

1153652

ZKSC8
Zinc finger protein with KRAB and SCAN domains 8

2

19

High-throughput

0.811

High

1380369

ZN232
Zinc finger protein 232

2

20

High-throughput

0.811

High

1291996

ZSC30
Zinc finger and SCAN domain-containing protein 30

2

19

High-throughput

0.783

High

1246836

SCND3
SCAN domain-containing protein 3

2

20

High-throughput

0.726

High

517600

ZSC22
Zinc finger and SCAN domain-containing protein 22

1

20

High-throughput

0.698

High

1187278

ZSC23
Zinc finger and SCAN domain-containing protein 23

1

20

High-throughput

0.691

High

1143844

TCAL1
Transcription elongation factor A protein-like 1

3

0

High-throughput

0.638

High

1380360

CABP5
Calcium-binding protein 5

4

2

High-throughput

0.637

High

339818

KLF8
Krueppel-like factor 8

1

20

High-throughput

0.618

High

1118665

KLF9
Krueppel-like factor 9

1

20

High-throughput

0.618

High

1351115

SP7
Transcription factor Sp7

1

20

High-throughput

0.618

High

1380356

KLF16
Krueppel-like factor 16

1

20

High-throughput

0.618

High

1380374

KLF12
Krueppel-like factor 12

1

19

High-throughput

0.618

High

1380355

LXN
Latexin

3

1

High-throughput

0.616

High

389467

FINC
Fibronectin

3

1

High-throughput

0.604

High

386058

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

2

20

High-throughput

0.584

High

980988

H2B1C
Histone H2B type 1-C/E/F/G/I

2

3

High-throughput

0.584

High

998645

H31
Histone H3.1

2

13

High-throughput

0.584

High

1133585

NFIX
Nuclear factor 1 X-type

2

15

High-throughput

0.584

High

954875

PSA6
Proteasome subunit alpha type-6

2

0

High-throughput

0.580

High

1157848

DDB1
DNA damage-binding protein 1

1

3

High-throughput

0.575

High

1271965

ZN765
Zinc finger protein 765

1

18

High-throughput

0.575

High

1348718

ZSC18
Zinc finger and SCAN domain-containing protein 18

1

19

High-throughput

0.575

High

1380368

ZN215
Zinc finger protein 215

1

19

High-throughput

0.575

High

1234702

TYW3
tRNA wybutosine-synthesizing protein 3 homolog

2

1

High-throughput

0.574

High

1380359

TRI39
E3 ubiquitin-protein ligase TRIM39

1

18

High-throughput

0.573

High

1380365

I36RA
Interleukin-36 receptor antagonist protein

2

1

High-throughput

0.553

High

1380367

PARP4
Protein mono-ADP-ribosyltransferase PARP4

1

5

High-throughput

0.536

High

3640

A0A0S2Z6X0
Zinc finger with KRAB and SCAN domains 4 isoform 3

1

20

High-throughput

0.528

High

1232504

Q6FHY5
MEOX2 protein

1

9

High-throughput

0.515

High

1315429

P20D2
Xaa-Arg dipeptidase

1

0

High-throughput

0.513

High

185907

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

6

High-throughput

0.501

High

179734

MDM4
Protein Mdm4

1

3

High-throughput

0.481

High

894076

MEOX2
Homeobox protein MOX-2

1

9

High-throughput

0.481

High

143173

NFIB
Nuclear factor 1 B-type

1

14

High-throughput

0.479

High

191038

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

1

High-throughput

0.479

High

239980

SOX15
Transcription factor SOX-15

1

6

High-throughput

0.479

High

254399

CC14B
Dual specificity protein phosphatase CDC14B

1

2

High-throughput

0.479

High

474186

NFIC
Nuclear factor 1 C-type

1

15

High-throughput

0.479

High

487613

PARP1
Poly [ADP-ribose] polymerase 1

1

5

High-throughput

0.479

High

662262

PAX7
Paired box protein Pax-7

1

3

High-throughput

0.479

High

685296

PAX6
Paired box protein Pax-6

1

3

High-throughput

0.479

High

697211

APEX1
DNA repair nuclease/redox regulator APEX1

1

1

High-throughput

0.479

High

703182

TEAD1
Transcriptional enhancer factor TEF-1

1

1

High-throughput

0.479

High

725301

TLX1
T-cell leukemia homeobox protein 1

1

8

High-throughput

0.479

High

800023

COIL
Coilin

1

3

High-throughput

0.479

High

877541

LHX1
LIM/homeobox protein Lhx1

1

5

High-throughput

0.479

High

883646

CENPA
Histone H3-like centromeric protein A

1

13

High-throughput

0.479

High

887088

CEBPA
CCAAT/enhancer-binding protein alpha

1

5

High-throughput

0.479

High

979117

RS6
Small ribosomal subunit protein eS6

1

5

High-throughput

0.479

High

1017086

H33
Histone H3.3

1

13

High-throughput

0.479

High

1087922

NFIA
Nuclear factor 1 A-type

1

14

High-throughput

0.479

High

1097466

CBX3
Chromobox protein homolog 3

1

20

High-throughput

0.479

High

1113921

CUL3
Cullin-3

1

20

High-throughput

0.479

High

1313317

SMC5
Structural maintenance of chromosomes protein 5

1

2

High-throughput

0.479

High

1380347

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

3

High-throughput

0.479

High

1380348

RNF31
E3 ubiquitin-protein ligase RNF31

1

12

High-throughput

0.479

High

1380352

FEV
Protein FEV

1

2

High-throughput

0.479

High

1380363

VSX1
Visual system homeobox 1

1

5

High-throughput

0.479

High

1380372

ZN330
Zinc finger protein 330

1

4

High-throughput

0.479

High

1149953

TERF2
Telomeric repeat-binding factor 2

1

0

High-throughput

0.458

High

1380357

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.458

High

189239

IPO8
Importin-8

1

20

High-throughput

0.445

High

207612

DHX15
ATP-dependent RNA helicase DHX15

1

1

High-throughput

0.445

High

289644

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

5

High-throughput

0.445

High

949414

EIF3E
Eukaryotic translation initiation factor 3 subunit E

1

1

High-throughput

0.445

High

1100196

TIF1B
Transcription intermediary factor 1-beta

1

20

High-throughput

0.445

High

1121840

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

1

High-throughput

0.445

High

1138479

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.445

High

1323118

CCAR2
Cell cycle and apoptosis regulator protein 2

1

6

High-throughput

0.445

High

1369730

RAD50
DNA repair protein RAD50

1

4

High-throughput

0.445

High

1380353

ANM1
Protein arginine N-methyltransferase 1

1

4

High-throughput

0.445

High

1092473

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

3

Small-scale

0.439

High

505395

U17L7
Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7

1

4

High-throughput

0.437

High

250750

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

0

High-throughput

0.426

High

1380370

EIF3L
Eukaryotic translation initiation factor 3 subunit L

1

0

High-throughput

0.426

High

141605

DDX3X
ATP-dependent RNA helicase DDX3X

1

2

High-throughput

0.407

High

441498

AGAL
Alpha-galactosidase A

1

2

High-throughput

0.407

High

939401

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

1

High-throughput

0.407

High

1012915

RT09
Small ribosomal subunit protein uS9m

1

8

High-throughput

0.407

High

1102882

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

3

High-throughput

0.407

High

1380373

TCAF1
TRPM8 channel-associated factor 1

1

3

High-throughput

0.407

High

1380366

OSGI1
Oxidative stress-induced growth inhibitor 1

2

0

High-throughput

0.316

High

1380358

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

0

High-throughput

0.261

Low

1380371

RT23
Small ribosomal subunit protein mS23

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025