HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: NU153 (P49790)
Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153)
Gene: NUP153

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	10202161, 37516964
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005635 - nuclear envelope GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005829 - cytosol GO:0006913 - nucleocytoplasmic transport and 2 others more... GO:0016020 - membrane GO:0031965 - nuclear membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1071 Hs			1 1475
+	Hs
		162518 XPO1_HUMAN (1-1071): 0: 1022: 100.00		RBP2_HUMAN (573-1152): 6.9e-53: 207: 19.12
+	Hs
		63864 XPO1_HUMAN (1-1071): 0: 1022: 100.00		RGPD3_HUMAN (1136-1440): 4.22e-38: 158: 16.39
+	Hs
		152753 XPO1_HUMAN (1-1071): 0: 1022: 100.00		RGPD8_HUMAN (1136-1440): 1.82e-37: 156: 16.72
+	Hs
		162448 XPO1_HUMAN (1-1071): 0: 1022: 100.00		NU214_HUMAN (146-1306): 4.07e-29: 129: 11.13
+	Xl
		48767 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		A0JMU3_XENLA (557-830): 4.86e-31: 135: 16.99
+	Hs
		163419 XPO1_HUMAN (1-1071): 0: 1022: 100.00		ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89
+	Hs
		162534 XPO1_HUMAN (1-1071): 0: 1022: 100.00		NUP98_HUMAN (749-1368): 8.75e-11: 69.1: 12.83
+	Dm
		1353152 XPO1_DROME (4-1071): 0: 905: 70.72		Q9VLS7_DROME (83-1183): 2.17e-23: 110: 9.02
+	Hs
		834652 TNPO1_HUMAN (33-1045): 1.81e-132: 425: 13.84		NU153_HUMAN (1-1475): 2.98e-176: 568: 100.00
+	Hs
		155550 TNPO2_HUMAN (33-1045): 7.78e-129: 415: 14.41		NU153_HUMAN (1-1475): 2.98e-176: 568: 100.00
+	Dm
		1353157 XPO1_DROME (4-1071): 0: 905: 70.72		NU214_DROME (72-907): 3.82e-10: 67.1: 8.85
+	Sc
		595000 XPO1_YEAST (14-1067): 0: 848: 46.08		NUP1_YEAST (863-1451): 7.24e-23: 108: 18.05
+	Sc
		541850 XPO1_YEAST (14-1067): 0: 848: 46.08		NSP1_YEAST (861-1373): 2.64e-12: 73.7: 18.15
+	Tt
		101847 G0RZB7_CHATD (22-1068): 0: 819: 48.14		NU145_CHATD (865-1304): 7.3e-09: 62.9: 15.28
+	Xl
		1137359 Q5U4V0_XENLA (33-1045): 8.68e-130: 418: 13.75		NU153_XENLA (15-1466): 1.12e-82: 302: 36.55
+	Hs
		834809 TNPO1_HUMAN (33-1045): 1.81e-132: 425: 13.84		RBP2_HUMAN (573-1152): 6.9e-53: 207: 19.12
+	Hs
		1273208 TNPO1_HUMAN (33-1045): 1.81e-132: 425: 13.84		RGPD5_HUMAN (1136-1440): 7.32e-39: 161: 16.72
+	Hs
		727300 TNPO1_HUMAN (33-1045): 1.81e-132: 425: 13.84		NU214_HUMAN (146-1306): 4.07e-29: 129: 11.13
+	Hs
		1273237 TNPO1_HUMAN (33-1045): 1.81e-132: 425: 13.84		ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89
+	Hs
		858024 TNPO1_HUMAN (33-1045): 1.81e-132: 425: 13.84		NUP98_HUMAN (749-1368): 8.75e-11: 69.1: 12.83