HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: AP1S1 (P61966)
AP-1 complex subunit sigma-1A (Adaptor protein complex AP-1 subunit sigma-1A) (Adaptor-related protein complex 1 subunit sigma-1A) (Clathrin assembly protein complex 1 sigma-1A small chain) (Clathrin coat assembly protein AP19) (Golgi adaptor HA1/AP1 adaptin sigma-1A subunit) (HA1 19 kDa subunit) (Sigma 1a subunit of AP-1 clathrin) (Sigma-adaptin 1A) (Sigma1A-adaptin)
Gene: AP1S1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26673895
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1071 Hs			1 158
+	Hs
		162555 XPO1_HUMAN (1-1071): 0: 1022: 100.00		AP1S2_HUMAN (2-157): 6.27e-54: 169: 87.82
+	Hs
		163067 XPO1_HUMAN (1-1071): 0: 1022: 100.00		AP3S1_HUMAN (1-146): 3.41e-50: 160: 36.18
+	Hs
		163116 XPO1_HUMAN (1-1071): 0: 1022: 100.00		AP2M1_HUMAN (1-158): 6.58e-47: 159: 16.98
+	Hs
		162560 XPO1_HUMAN (1-1071): 0: 1022: 100.00		AP3S2_HUMAN (1-145): 1.14e-48: 157: 37.09
+	Hs
		163228 XPO1_HUMAN (1-1071): 0: 1022: 100.00		AP1M1_HUMAN (3-154): 3.03e-45: 154: 18.07
+	Xl
		1140117 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q5XGM9_XENLA (2-157): 4.68e-52: 164: 84.91
+	Xl
		1155739 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		AP2M1_XENLA (1-158): 3.83e-47: 160: 16.98
+	Xl
		1155750 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q8AVV3_XENLA (1-146): 8.25e-50: 160: 36.84
+	Hs
		162572 XPO1_HUMAN (1-1071): 0: 1022: 100.00		COPZ1_HUMAN (2-152): 1.21e-43: 143: 19.61
+	Xl
		1129163 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q5M7C4_XENLA (1-146): 1.03e-48: 157: 36.18
+	Xl
		1118800 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q4V857_XENLA (3-154): 2.4e-45: 155: 18.07
+	Sc
		676172 XPO1_YEAST (14-1067): 0: 848: 46.08		AP3S_YEAST (1-158): 4.99e-45: 147: 27.27
+	Sc
		675945 XPO1_YEAST (14-1067): 0: 848: 46.08		AP1S1_YEAST (2-149): 4.84e-43: 141: 53.33
+	Sc
		676282 XPO1_YEAST (14-1067): 0: 848: 46.08		AP2S_YEAST (2-141): 1.76e-42: 140: 38.89
+	Mm
		1322190 XPO7_MOUSE (23-1013): 5.43e-120: 397: 13.01		AP3S1_MOUSE (1-146): 3.41e-50: 160: 36.18