HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: RN138 (Q8WVD3)
E3 ubiquitin-protein ligase RNF138 (EC 2.3.2.27) (Nemo-like kinase-associated RING finger protein) (NLK-associated RING finger protein) (hNARF) (RING finger protein 138) (RING-type E3 ubiquitin transferase RNF138)
Gene: RNF138

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26673895
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1071 Hs			1 245
+	Hs
		162683 XPO1_HUMAN (1-1071): 0: 1022: 100.00		TRI26_HUMAN (4-239): 2.73e-33: 127: 15.64
+	Hs
		163239 XPO1_HUMAN (1-1071): 0: 1022: 100.00		TRIM5_HUMAN (5-160): 2.04e-28: 113: 14.91
+	Hs
		163177 XPO1_HUMAN (1-1071): 0: 1022: 100.00		RING2_HUMAN (2-188): 8.11e-29: 112: 18.72
+	Hs
		163395 XPO1_HUMAN (1-1071): 0: 1022: 100.00		KCMF1_HUMAN (147-236): 1.38e-25: 105: 32.22
+	Xl
		69129 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		A9JSS1_XENLA (2-187): 3.1e-27: 108: 16.67
+	Hs
		162658 XPO1_HUMAN (1-1071): 0: 1022: 100.00		RING1_HUMAN (2-74): 3.94e-21: 92.7: 27.40
+	Xl
		1151533 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		KCMF1_XENLA (147-236): 6.97e-26: 105: 32.22
+	Hs
		207985 XPOT_HUMAN (29-1023): 3.55e-126: 410: 14.85		RING2_HUMAN (2-188): 8.11e-29: 112: 18.72
+	Hs
		1060982 IMB1_HUMAN (27-908): 2.89e-90: 311: 11.32		TRAF6_HUMAN (12-245): 1.55e-33: 128: 16.25
+	Dm
		1279453 X2JDN0_DROME (23-498): 5.05e-54: 207: 13.90		KCMF1_DROME (147-235): 9.3e-27: 110: 31.46