HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: AP3S1 (Q92572)
AP-3 complex subunit sigma-1 (AP-3 complex subunit sigma-3A) (Adaptor-related protein complex 3 subunit sigma-1) (Clathrin-associated/assembly/adaptor protein, small 3) (Sigma-3A-adaptin) (Sigma3A-adaptin) (Sigma-adaptin 3a)
Gene: AP3S1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26673895
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1071 Hs			1 193
+	Hs
		162560 XPO1_HUMAN (1-1071): 0: 1022: 100.00		AP3S2_HUMAN (1-192): 1.95e-71: 216: 84.38
+	Xl
		1155750 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q8AVV3_XENLA (1-193): 2.74e-75: 226: 97.41
+	Xl
		1129163 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q5M7C4_XENLA (1-192): 3.65e-72: 218: 84.38
+	Hs
		162577 XPO1_HUMAN (1-1071): 0: 1022: 100.00		AP1S1_HUMAN (1-158): 9.45e-51: 162: 34.81
+	Hs
		162555 XPO1_HUMAN (1-1071): 0: 1022: 100.00		AP1S2_HUMAN (2-158): 5.07e-50: 160: 35.03
+	Hs
		163116 XPO1_HUMAN (1-1071): 0: 1022: 100.00		AP2M1_HUMAN (1-186): 6.1e-47: 160: 11.83
+	Hs
		163499 XPO1_HUMAN (1-1071): 0: 1022: 100.00		AP3M1_HUMAN (1-188): 1.37e-44: 154: 18.09
+	Hs
		162572 XPO1_HUMAN (1-1071): 0: 1022: 100.00		COPZ1_HUMAN (2-166): 7.56e-45: 148: 22.02
+	Xl
		1155739 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		AP2M1_XENLA (1-186): 3.03e-47: 161: 11.83
+	Xl
		1140117 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q5XGM9_XENLA (2-166): 2.56e-49: 159: 35.15
+	Xl
		1150206 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q6DDI4_XENLA (3-186): 5.01e-42: 147: 15.76
+	Sc
		675945 XPO1_YEAST (14-1067): 0: 848: 46.08		AP1S1_YEAST (2-152): 1.71e-47: 154: 33.33
+	Sc
		676172 XPO1_YEAST (14-1067): 0: 848: 46.08		AP3S_YEAST (1-153): 1.44e-46: 153: 44.24
+	Sc
		676282 XPO1_YEAST (14-1067): 0: 848: 46.08		AP2S_YEAST (2-148): 4.03e-47: 152: 38.00
+	Mm
		1322190 XPO7_MOUSE (23-1013): 5.43e-120: 397: 13.01		AP3S1_MOUSE (1-193): 7.1e-75: 224: 100.00