HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: PD1L1 (Q9NZQ7)
Programmed cell death 1 ligand 1 (PD-L1) (PDCD1 ligand 1) (Programmed death ligand 1) (hPD-L1) (B7 homolog 1) (B7-H1) (CD antigen CD274)
Gene: CD274

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36376293
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1071 Hs			1 290
+	Hs
		163148 XPO1_HUMAN (1-1071): 0: 1022: 100.00		VSIG2_HUMAN (3-270): 3.76e-40: 144: 15.11
+	Hs
		162619 XPO1_HUMAN (1-1071): 0: 1022: 100.00		CXAR_HUMAN (3-281): 2.19e-39: 143: 16.67
+	Hs
		1117742 Q4LE60_HUMAN (33-1045): 1.11e-138: 446: 14.83		PD1L1_HUMAN (1-290): 1.08e-62: 201: 100.00
+	Hs
		1273232 TNPO1_HUMAN (33-1045): 1.81e-132: 425: 13.84		PD1L1_HUMAN (1-290): 1.08e-62: 201: 100.00
+	Hs
		155653 TNPO2_HUMAN (33-1045): 7.78e-129: 415: 14.41		PD1L1_HUMAN (1-290): 1.08e-62: 201: 100.00
+	Hs
		208015 XPOT_HUMAN (29-1023): 3.55e-126: 410: 14.85		PD1L1_HUMAN (1-290): 1.08e-62: 201: 100.00
+	Hs
		1349379 XPO7_HUMAN (23-1013): 1.48e-120: 398: 13.18		PD1L1_HUMAN (1-290): 1.08e-62: 201: 100.00
+	Hs
		1166522 TNPO1_HUMAN (33-1045): 1.81e-132: 425: 13.84		BTNL9_HUMAN (14-289): 1.23e-48: 171: 14.44
+	Hs
		1117739 Q4LE60_HUMAN (33-1045): 1.11e-138: 446: 14.83		VSIG2_HUMAN (3-270): 3.76e-40: 144: 15.11
+	Hs
		155590 TNPO2_HUMAN (33-1045): 7.78e-129: 415: 14.41		BTNL9_HUMAN (14-289): 1.23e-48: 171: 14.44
+	Hs
		1166570 XPO7_HUMAN (23-1013): 1.48e-120: 398: 13.18		BTNL9_HUMAN (14-289): 1.23e-48: 171: 14.44
+	Hs
		1273203 TNPO1_HUMAN (33-1045): 1.81e-132: 425: 13.84		VSIG2_HUMAN (3-270): 3.76e-40: 144: 15.11
+	Hs
		155624 TNPO2_HUMAN (33-1045): 7.78e-129: 415: 14.41		VSIG2_HUMAN (3-270): 3.76e-40: 144: 15.11
+	Hs
		1294596 XPO7_HUMAN (23-1013): 1.48e-120: 398: 13.18		VSIG2_HUMAN (3-270): 3.76e-40: 144: 15.11
+	Hs
		155541 TNPO2_HUMAN (33-1045): 7.78e-129: 415: 14.41		CD80_HUMAN (28-259): 6.01e-30: 116: 21.07
+	Hs
		706937 XPO7_HUMAN (23-1013): 1.48e-120: 398: 13.18		CD80_HUMAN (28-259): 6.01e-30: 116: 21.07
+	Hs
		1060948 IMB1_HUMAN (27-908): 2.89e-90: 311: 11.32		PD1L1_HUMAN (1-290): 1.08e-62: 201: 100.00
+	Hs
		1294594 XPO5_HUMAN (26-665): 5.8e-100: 344: 16.12		VSIG2_HUMAN (3-270): 3.76e-40: 144: 15.11
+	Hs
		1060791 IMB1_HUMAN (27-908): 2.89e-90: 311: 11.32		BTNL9_HUMAN (14-289): 1.23e-48: 171: 14.44
+	Hs
		706940 TNPO3_HUMAN (24-901): 9.93e-89: 307: 14.37		CD80_HUMAN (28-259): 6.01e-30: 116: 21.07