HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: NXF1 (Q9UBU9)
Nuclear RNA export factor 1 (Tip-associated protein) (Tip-associating protein) (mRNA export factor TAP)
Gene: NXF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	35271311, 37516964, 10668806
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol and 1 others more... GO:0006406 - mRNA export from nucleus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1071 Hs			1 619
+	Xl
		1153622 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q6IRQ2_XENLA (1-619): 0: 752: 55.29
+	Hs
		163273 XPO1_HUMAN (1-1071): 0: 1022: 100.00		NXF3_HUMAN (9-573): 0: 670: 48.41
+	Hs
		1273235 TNPO1_HUMAN (33-1045): 1.81e-132: 425: 13.84		NXF1_HUMAN (1-619): 0: 929: 100.00
+	Hs
		155656 TNPO2_HUMAN (33-1045): 7.78e-129: 415: 14.41		NXF1_HUMAN (1-619): 0: 929: 100.00
+	Hs
		1060955 IMB1_HUMAN (27-908): 2.89e-90: 311: 11.32		NXF1_HUMAN (1-619): 0: 929: 100.00
+	Hs
		162235 XPO1_HUMAN (1-1071): 0: 1022: 100.00		CF410_HUMAN (260-357): 2.35e-23: 101: 30.30
+	Xl
		1148398 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q68EZ7_XENLA (260-357): 5.86e-21: 94.5: 28.28