Protein: PBX1
Pre-B-cell leukemia transcription factor 1 (Homeobox protein PBX1) (Homeobox protein PRL)

Gene: PBX1
Organism: Homo sapiens
Interactions: 77
UniProt ID: P40424

Gene Ontology (top 5):
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

823829

PKNX1
Homeobox protein PKNOX1

11

20

Small-scale

0.978

High

163415

MEIS2
Homeobox protein Meis2

9

19

Small-scale

0.972

High

137124

MEIS1
Homeobox protein Meis1

7

19

Small-scale

0.953

High

253005

LMX1B
LIM homeobox transcription factor 1-beta

3

9

High-throughput

0.861

High

725025

HXC8
Homeobox protein Hox-C8

3

20

Small-scale

0.843

High

574042

HXB1
Homeobox protein Hox-B1

2

20

Small-scale

0.785

High

823858

PKNX2
Homeobox protein PKNOX2

2

20

High-throughput

0.783

High

478660

HXB5
Homeobox protein Hox-B5

2

20

High-throughput

0.783

High

823830

HXC5
Homeobox protein Hox-C5

2

20

High-throughput

0.783

High

484820

HXB7
Homeobox protein Hox-B7

1

20

Small-scale

0.740

High

724922

HXA10
Homeobox protein Hox-A10

1

20

Small-scale

0.724

High

184763

SHOX
Short stature homeobox protein

1

20

High-throughput

0.691

High

576182

PO2F1
POU domain, class 2, transcription factor 1

1

5

Small-scale

0.681

High

724988

HXA9
Homeobox protein Hox-A9

1

20

Small-scale

0.681

High

823824

MAGA1
Melanoma-associated antigen 1

3

7

High-throughput

0.667

High

823838

MB211
Putative nucleotidyltransferase MAB21L1

3

9

High-throughput

0.667

High

823867

MB212
Protein mab-21-like 2

3

9

High-throughput

0.667

High

725215

TLX1
T-cell leukemia homeobox protein 1

1

20

Small-scale

0.653

High

478283

HXD4
Homeobox protein Hox-D4

1

20

Small-scale

0.647

High

604772

HXB8
Homeobox protein Hox-B8

1

20

Small-scale

0.647

High

703235

HXD9
Homeobox protein Hox-D9

1

20

Small-scale

0.647

High

823827

PDX1
Pancreas/duodenum homeobox protein 1

1

20

Small-scale

0.647

High

139387

VMA5A
von Willebrand factor A domain-containing protein 5A

2

5

High-throughput

0.628

High

823850

DAAF8
Dynein axonemal assembly factor 8

2

5

High-throughput

0.628

High

823836

FOXC1
Forkhead box protein C1

2

15

Small-scale

0.628

High

209960

CRX
Cone-rod homeobox protein

1

16

High-throughput

0.618

High

823840

HDAC1
Histone deacetylase 1

2

5

Small-scale

0.611

High

823839

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

2

1

High-throughput

0.606

High

823843

BRM1L
Breast cancer metastasis-suppressor 1-like protein

2

7

High-throughput

0.606

High

823856

CDA7L
Cell division cycle-associated 7-like protein

2

1

High-throughput

0.606

High

823822

PBX2
Pre-B-cell leukemia transcription factor 2

1

20

Small-scale

0.584

High

823845

F222A
Protein FAM222A

2

5

High-throughput

0.574

High

823847

CE024
UPF0461 protein C5orf24

2

5

High-throughput

0.574

High

823857

CC120
Coiled-coil domain-containing protein 120

2

6

High-throughput

0.574

High

823854

KAT2A
Histone acetyltransferase KAT2A

1

2

Small-scale

0.561

High

823842

EFHC1
EF-hand domain-containing protein 1

2

1

High-throughput

0.553

High

823849

F90A1
Protein FAM90A1

2

2

High-throughput

0.553

High

133091

FOXE1
Forkhead box protein E1

1

14

High-throughput

0.536

High

823828

FOXA1
Hepatocyte nuclear factor 3-alpha

1

14

High-throughput

0.536

High

823832

SUH
Recombining binding protein suppressor of hairless

1

2

High-throughput

0.536

High

823862

FOXQ1
Forkhead box protein Q1

1

15

High-throughput

0.536

High

823863

TSH2
Teashirt homolog 2

1

5

High-throughput

0.536

High

823864

M3K20
Mitogen-activated protein kinase kinase kinase 20

1

4

High-throughput

0.536

High

823868

SRPRB
Signal recognition particle receptor subunit beta

1

2

High-throughput

0.536

High

563351

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

Small-scale

0.515

High

773117

MYH10
Myosin-10

1

1

Small-scale

0.515

High

823831

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.513

High

507633

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

High-throughput

0.501

High

823846

SMRD3
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3

1

4

Small-scale

0.501

High

823853

CBP
CREB-binding protein

1

2

Small-scale

0.501

High

823865

TMOD3
Tropomodulin-3

1

3

High-throughput

0.489

High

823859

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

1

Small-scale

0.481

High

142877

NFIB
Nuclear factor 1 B-type

1

6

High-throughput

0.479

High

188196

HDAC3
Histone deacetylase 3

1

5

Small-scale

0.479

High

274290

SIN3B
Paired amphipathic helix protein Sin3b

1

6

Small-scale

0.479

High

403887

GCR
Glucocorticoid receptor

1

8

Small-scale

0.479

High

473834

NFIC
Nuclear factor 1 C-type

1

7

High-throughput

0.479

High

555925

CADH1
Cadherin-1

1

1

Small-scale

0.479

High

581628

MYOD1
Myoblast determination protein 1

1

3

Small-scale

0.479

High

823823

CDN2B
Cyclin-dependent kinase 4 inhibitor B

1

4

Small-scale

0.479

High

823825

GATA4
Transcription factor GATA-4

1

4

High-throughput

0.479

High

823826

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

3

Small-scale

0.479

High

823833

MN1
Transcriptional activator MN1

1

1

Small-scale

0.479

High

823834

NFIA
Nuclear factor 1 A-type

1

6

High-throughput

0.479

High

823835

TRI26
Tripartite motif-containing protein 26

1

1

Small-scale

0.479

High

823837

TRAF1
TNF receptor-associated factor 1

1

5

Small-scale

0.479

High

823841

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

Small-scale

0.479

High

823848

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

1

Small-scale

0.479

High

823851

SP7
Transcription factor Sp7

1

6

High-throughput

0.479

High

823852

ESR2
Estrogen receptor beta

1

8

High-throughput

0.479

High

823855

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

1

Small-scale

0.479

High

823860

CIC
Protein capicua homolog

1

12

High-throughput

0.479

High

823861

TBX5
T-box transcription factor TBX5

1

12

High-throughput

0.479

High

823844

UBR4
E3 ubiquitin-protein ligase UBR4

1

0

Small-scale

0.458

High

366473

UROK
Urokinase-type plasminogen activator

1

2

Small-scale

0.437

High

823866

GRHL1
Grainyhead-like protein 1 homolog

1

0

High-throughput

0.426

High

416954

CY24B
NADPH oxidase 2

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025