HitPredict

Interactor 1: AT2A1 (O14983)
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (SERCA1) (SR Ca(2+)-ATPase 1) (EC 7.2.2.10) (Calcium pump 1) (Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase)
Gene: ATP2A1

Interactor 2: NB5R1 (Q9UHQ9)
NADH-cytochrome b5 reductase 1 (b5R.1) (EC 1.6.2.2) (Humb5R2) (NAD(P)H:quinone oxidoreductase type 3 polypeptide A2)
Gene: CYB5R1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	34079125, 33961781
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005789 - endoplasmic reticulum membrane GO:0016020 - membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1001 Hs			1 305
+	Hs
		163716 AT2A1_HUMAN (1-1001): 0: 977: 100.00		NB5R3_HUMAN (1-305): 1.65e-117: 342: 59.02
+	Hs
		1274550 AT2A3_HUMAN (1-999): 0: 950: 75.88		NB5R1_HUMAN (1-305): 1.26e-123: 357: 100.00
+	Hs
		335356 AT2A2_HUMAN (1-1000): 0: 950: 83.40		NB5R3_HUMAN (1-305): 1.65e-117: 342: 59.02
+	Hs
		163738 AT2A1_HUMAN (1-1001): 0: 977: 100.00		NCPR_HUMAN (11-293): 2.03e-64: 216: 14.24
+	Hs
		561509 AT2A2_HUMAN (1-1000): 0: 950: 83.40		NOS2_HUMAN (18-302): 1.49e-63: 218: 14.61
+	Oc
		1167906 AT1A1_RABIT (2-998): 0: 800: 26.10		Q6Y5E2_RABIT (24-290): 4.86e-53: 188: 15.79
+	Hs
		619199 AT2B4_HUMAN (5-993): 0: 761: 25.05		NOS3_HUMAN (18-303): 2.82e-61: 212: 16.12