HitPredict

Interactor 1: ZN609 (O15014)
Zinc finger protein 609
Gene: ZNF609

Interactor 2: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35140242, 23667531
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1411 Hs			1 317
+	Hs
		164193 ZN609_HUMAN (1-1411): 0: 660: 100.00		SOX5_HUMAN (2-127): 7.91e-43: 158: 41.27
+	Hs
		164200 ZN609_HUMAN (1-1411): 0: 660: 100.00		SOX9_HUMAN (28-260): 2.6e-37: 140: 27.57
+	Hs
		164270 ZN609_HUMAN (1-1411): 0: 660: 100.00		SOX17_HUMAN (7-260): 1.35e-34: 132: 28.19
+	Hs
		164207 ZN609_HUMAN (1-1411): 0: 660: 100.00		SOX10_HUMAN (28-219): 8.75e-34: 130: 35.42
+	Hs
		164264 ZN609_HUMAN (1-1411): 0: 660: 100.00		SOX7_HUMAN (23-299): 8.76e-34: 129: 27.03
+	Hs
		164194 ZN609_HUMAN (1-1411): 0: 660: 100.00		SOX6_HUMAN (29-244): 2.42e-29: 120: 23.61
+	Hs
		164167 ZN609_HUMAN (1-1411): 0: 660: 100.00		SOX15_HUMAN (13-118): 1.78e-31: 119: 66.04
+	Hs
		818597 ZN608_HUMAN (7-1411): 3.46e-100: 354: 37.03		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		727826 ZN608_HUMAN (7-1411): 3.46e-100: 354: 37.03		SOX5_HUMAN (2-127): 7.91e-43: 158: 41.27
+	Hs
		881833 ZN608_HUMAN (7-1411): 3.46e-100: 354: 37.03		SOX10_HUMAN (28-219): 8.75e-34: 130: 35.42
+	Hs
		1311939 ZN608_HUMAN (7-1411): 3.46e-100: 354: 37.03		SOX7_HUMAN (23-299): 8.76e-34: 129: 27.03
+	Hs
		225802 ZN608_HUMAN (7-1411): 3.46e-100: 354: 37.03		SOX15_HUMAN (13-118): 1.78e-31: 119: 66.04
+	Hs
		818155 NIPBL_HUMAN (353-1350): 1.47e-56: 219: 10.59		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		996715 NIPBL_HUMAN (353-1350): 1.47e-56: 219: 10.59		SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68
+	Hs
		818266 KMT2C_HUMAN (409-1235): 3.4e-15: 83.7: 11.72		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		1056996 MDC1_HUMAN (55-885): 1.17e-32: 140: 11.66		TF7L2_HUMAN (14-255): 5.81e-35: 135: 19.75
+	Hs
		331812 MDC1_HUMAN (55-885): 1.17e-32: 140: 11.66		NSD2_HUMAN (7-251): 1.34e-29: 120: 10.71
+	Hs
		818819 KMT2C_HUMAN (409-1235): 3.4e-15: 83.7: 11.72		SOX9_HUMAN (28-260): 2.6e-37: 140: 27.57
+	Hs
		1243843 KMT2C_HUMAN (409-1235): 3.4e-15: 83.7: 11.72		SOX17_HUMAN (7-260): 1.35e-34: 132: 28.19
+	Hs
		1243837 KMT2C_HUMAN (409-1235): 3.4e-15: 83.7: 11.72		SOX7_HUMAN (23-299): 8.76e-34: 129: 27.03