Protein: FA8
Coagulation factor VIII (Antihemophilic factor) (AHF) (Procoagulant component) [Cleaved into: Factor VIIIa heavy chain, 200 kDa isoform; Factor VIIIa heavy chain, 92 kDa isoform; Factor VIII B chain; Factor VIIIa light chain]

Gene: FA8, F8
Organism: Homo sapiens
Interactions: 27
UniProt ID: P00451

Gene Ontology (top 5):
GO:0005507 - copper ion binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005788 - endoplasmic reticulum lumen
GO:0005796 - Golgi lumen

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

361566

VWF
von Willebrand factor

4

1

Small-scale

0.893

High

361561

FA8
Coagulation factor VIII

1

11

Small-scale

0.647

High

361565

KV320
Immunoglobulin kappa variable 3-20

1

0

Small-scale

0.614

High

361578

RYBP
RING1 and YY1-binding protein

2

2

High-throughput

0.567

High

361563

FA9
Coagulation factor IX

1

16

Small-scale

0.527

High

361568

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

2

High-throughput

0.515

High

361562

THRB
Prothrombin

1

12

Small-scale

0.501

High

361564

FA10
Coagulation factor X

1

12

Small-scale

0.501

High

361567

PROS
Vitamin K-dependent protein S

1

9

Small-scale

0.501

High

361581

GGA1
ADP-ribosylation factor-binding protein GGA1

1

2

High-throughput

0.494

High

361582

UBQL1
Ubiquilin-1

1

2

High-throughput

0.481

High

361576

LRP1
Prolow-density lipoprotein receptor-related protein 1

1

0

Small-scale

0.480

High

361577

ATS13
A disintegrin and metalloproteinase with thrombospondin motifs 13

1

0

Small-scale

0.480

High

361571

CALX
Calnexin

1

10

Small-scale

0.479

High

361572

MYH9
Myosin-9

1

8

High-throughput

0.479

High

361573

LMAN1
Protein ERGIC-53

1

1

Small-scale

0.479

High

361579

MAGB6
Melanoma-associated antigen B6

1

1

High-throughput

0.470

High

361569

HIS3
Histatin-3

1

0

Small-scale

0.458

High

273248

T22D2
TSC22 domain family protein 2

1

1

Small-scale

0.439

High

72977

WDR64
WD repeat-containing protein 64

1

2

High-throughput

0.437

High

361570

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

3

High-throughput

0.437

High

165755

PAHX
Phytanoyl-CoA dioxygenase, peroxisomal

1

0

Small-scale

0.299

High

361575

RL18A
Large ribosomal subunit protein eL20

1

0

High-throughput

0.269

Low

254497

EIF1B
Eukaryotic translation initiation factor 1b

1

0

High-throughput

0.249

Low

361574

BRCA2
Breast cancer type 2 susceptibility protein

1

0

Small-scale

0.249

Low

361580

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025