HitPredict

Interactor 1: SPTN2 (O15020)
Spectrin beta chain, non-erythrocytic 2 (Beta-III spectrin) (Spinocerebellar ataxia 5 protein)
Gene: SPTBN2

Interactor 2: PCNT (O95613)
Pericentrin (Kendrin) (Pericentrin-B)
Gene: PCNT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	35914814
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2390 Hs			1 3336
+	Hs
		317230 SPTB2_HUMAN (3-2390): 0: 712: 61.09		PCNT_HUMAN (1-3336): 0: 718: 100.00
+	Hs
		317220 UTRN_HUMAN (19-2308): 3.65e-86: 318: 14.19		PCNT_HUMAN (1-3336): 0: 718: 100.00
+	Hs
		317246 SPTN1_HUMAN (279-2273): 5.34e-78: 291: 18.75		PCNT_HUMAN (1-3336): 0: 718: 100.00
+	Hs
		317252 PLEC_HUMAN (379-2232): 1.33e-50: 201: 10.46		PCNT_HUMAN (1-3336): 0: 718: 100.00
+	Hs
		164575 SPTN2_HUMAN (1-2390): 0: 715: 100.00		MYH9_HUMAN (2690-3313): 1.18e-18: 96.7: 9.89
+	Hs
		724781 SPTB2_HUMAN (3-2390): 0: 712: 61.09		MYH9_HUMAN (2690-3313): 1.18e-18: 96.7: 9.89
+	Hs
		360660 SPTA1_HUMAN (182-1386): 5.78e-93: 340: 19.37		CP250_HUMAN (1630-3336): 3.41e-53: 210: 10.43
+	Hs
		969584 SPTN1_HUMAN (279-2273): 5.34e-78: 291: 18.75		CENPE_HUMAN (1328-3305): 2.89e-65: 250: 10.28
+	Dm
		527099 SPTCA_DROME (279-2149): 2.74e-106: 383: 18.91		LVA_DROME (1967-3211): 1.36e-32: 142: 10.43
+	Hs
		211515 ACTN4_HUMAN (56-621): 3.25e-122: 412: 41.70		MYH9_HUMAN (2690-3313): 1.18e-18: 96.7: 9.89
+	Hs
		522612 SPTN1_HUMAN (279-2273): 5.34e-78: 291: 18.75		MYH7_HUMAN (2483-3316): 1.1e-33: 146: 12.07
+	Hs
		360644 SPTA1_HUMAN (182-1386): 5.78e-93: 340: 19.37		PLEC_HUMAN (2464-3115): 2.24e-12: 76.1: 14.83
+	Hs
		521484 ACTN1_HUMAN (31-766): 7.87e-88: 310: 32.02		MYH9_HUMAN (2690-3313): 1.18e-18: 96.7: 9.89
+	Hs
		724817 SPTN1_HUMAN (279-2273): 5.34e-78: 291: 18.75		MYH9_HUMAN (2690-3313): 1.18e-18: 96.7: 9.89
+	Hs
		1045418 SPTN1_HUMAN (279-2273): 5.34e-78: 291: 18.75		PLEC_HUMAN (2464-3115): 2.24e-12: 76.1: 14.83
+	Dm
		962674 SPTCB_DROME (265-2352): 5.42e-58: 225: 16.51		LVA_DROME (1967-3211): 1.36e-32: 142: 10.43
+	Dm
		1182584 Q7KV70_DROME (452-2383): 2.29e-53: 210: 15.05		LVA_DROME (1967-3211): 1.36e-32: 142: 10.43
+	Hs
		724839 PLEC_HUMAN (379-2232): 1.33e-50: 201: 10.46		MYH9_HUMAN (2690-3313): 1.18e-18: 96.7: 9.89
+	Hs
		1068536 PLEC_HUMAN (379-2232): 1.33e-50: 201: 10.46		PLEC_HUMAN (2464-3115): 2.24e-12: 76.1: 14.83
+	Mm
		513821 DMD_MOUSE (231-1491): 4.57e-15: 84.5: 10.70		PLEC_MOUSE (2-1335): 1.57e-39: 165: 10.63