HitPredict

Interactor 1: SC16A (O15027)
Protein transport protein Sec16A (SEC16 homolog A) (p250)
Gene: SEC16A

Interactor 2: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28065597
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0005789 - endoplasmic reticulum membrane GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 2357 Hs			1 1210
+	Hs
		338874 MINT_HUMAN (3-1242): 2.25e-12: 75.2: 13.32		EGFR_HUMAN (1-1210): 0: 1241: 100.00
+	Hs
		337875 MUC1_HUMAN (967-1439): 3.67e-10: 67.7: 9.90		EGFR_HUMAN (1-1210): 0: 1241: 100.00
+	Hs
		338878 MUC4_HUMAN (1198-2347): 3.15e-09: 65.1: 9.29		EGFR_HUMAN (1-1210): 0: 1241: 100.00
+	Hs
		338965 TARA_HUMAN (870-2322): 5.03e-09: 64.3: 9.42		EGFR_HUMAN (1-1210): 0: 1241: 100.00
+	Hs
		554307 MUC1_HUMAN (967-1439): 3.67e-10: 67.7: 9.90		ERBB4_HUMAN (1-1199): 0: 1137: 49.46
+	Hs
		1071005 MUC4_HUMAN (1198-2347): 3.15e-09: 65.1: 9.29		ERBB4_HUMAN (1-1199): 0: 1137: 49.46
+	Hs
		383583 MUC1_HUMAN (967-1439): 3.67e-10: 67.7: 9.90		ERBB2_HUMAN (5-1200): 0: 1111: 48.49
+	Hs
		383946 MUC4_HUMAN (1198-2347): 3.15e-09: 65.1: 9.29		ERBB2_HUMAN (5-1200): 0: 1111: 48.49
+	Hs
		302237 SC31A_HUMAN (26-347): 7.63e-09: 63.5: 12.31		ERBB2_HUMAN (5-1200): 0: 1111: 48.49
+	Hs
		554266 MUC1_HUMAN (967-1439): 3.67e-10: 67.7: 9.90		ERBB3_HUMAN (1-1210): 0: 1080: 40.95
+	Hs
		601984 MUC4_HUMAN (1198-2347): 3.15e-09: 65.1: 9.29		ERBB3_HUMAN (1-1210): 0: 1080: 40.95
+	Hs
		302241 SC31A_HUMAN (26-347): 7.63e-09: 63.5: 12.31		RET_HUMAN (420-1058): 5.61e-129: 425: 22.69
+	Rn
		88517 D3ZAP7_RAT (761-1273): 1.33e-12: 76.1: 11.30		INSR_RAT (579-1032): 2.5e-106: 367: 23.66
+	Rn
		102464 G3V699_RAT (6-327): 2.17e-10: 68.5: 13.50		INSR_RAT (579-1032): 2.5e-106: 367: 23.66
+	Hs
		554283 MUC1_HUMAN (967-1439): 3.67e-10: 67.7: 9.90		ZAP70_HUMAN (718-961): 5.57e-53: 199: 39.59
+	Hs
		302242 SC31A_HUMAN (26-347): 7.63e-09: 63.5: 12.31		IGF1R_HUMAN (354-658): 1.12e-14: 81.4: 18.47