Protein: CEAM8
Cell adhesion molecule CEACAM8 (CD67 antigen) (Carcinoembryonic antigen CGM6) (Carcinoembryonic antigen-related cell adhesion molecule 8) (CEA cell adhesion molecule 8) (Non-specific cross-reacting antigen NCA-95) (CD antigen CD66b)

Gene: CEAM8, CEACAM8
Organism: Homo sapiens
Interactions: 129
UniProt ID: P31997

Gene Ontology (top 5):
GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0006955 - immune response
GO:0007157 - heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0009986 - cell surface

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

567234

CEAM1
Cell adhesion molecule CEACAM1

2

17

Small-scale

0.834

High

731822

CEAM6
Cell adhesion molecule CEACAM6

2

19

Small-scale

0.825

High

731888

NGLY1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase

2

2

High-throughput

0.694

High

133171

QSOX1
Sulfhydryl oxidase 1

1

11

High-throughput

0.691

High

136597

MANBA
Beta-mannosidase

1

1

High-throughput

0.691

High

160811

TOR1B
Torsin-1B

1

2

High-throughput

0.691

High

183228

LAMA5
Laminin subunit alpha-5

1

16

High-throughput

0.691

High

249032

NRP2
Neuropilin-2

1

3

High-throughput

0.691

High

269836

IGSF3
Immunoglobulin superfamily member 3

1

17

High-throughput

0.691

High

283660

GPC4
Glypican-4

1

3

High-throughput

0.691

High

447989

ITAV
Integrin alpha-V

1

7

High-throughput

0.691

High

467820

BGLR
Beta-glucuronidase

1

1

High-throughput

0.691

High

599104

CBPE
Carboxypeptidase E

1

5

High-throughput

0.691

High

611708

BMP7
Bone morphogenetic protein 7

1

4

High-throughput

0.691

High

612042

ITB5
Integrin beta-5

1

7

High-throughput

0.691

High

625986

ITIH2
Inter-alpha-trypsin inhibitor heavy chain H2

1

4

High-throughput

0.691

High

654938

ITA6
Integrin alpha-6

1

7

High-throughput

0.691

High

731823

TNFL9
Tumor necrosis factor ligand superfamily member 9

1

1

High-throughput

0.691

High

731828

PLXA3
Plexin-A3

1

4

High-throughput

0.691

High

731830

ITA8
Integrin alpha-8 [Cleaved into: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain]

1

7

High-throughput

0.691

High

731831

CA2D1
Voltage-dependent calcium channel subunit alpha-2/delta-1

1

3

High-throughput

0.691

High

731832

EPHB4
Ephrin type-B receptor 4

1

11

High-throughput

0.691

High

731840

PTK7
Inactive tyrosine-protein kinase 7

1

20

High-throughput

0.691

High

731841

PTPRS
Receptor-type tyrosine-protein phosphatase S

1

16

High-throughput

0.691

High

731842

ADAM9
Disintegrin and metalloproteinase domain-containing protein 9

1

3

High-throughput

0.691

High

731843

ITA7
Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form]

1

7

High-throughput

0.691

High

731845

FAT1
Protocadherin Fat 1

1

13

High-throughput

0.691

High

731849

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

1

12

High-throughput

0.691

High

731855

SDK2
Protein sidekick-2

1

17

High-throughput

0.691

High

731856

FREM2
FRAS1-related extracellular matrix protein 2

1

18

High-throughput

0.691

High

731863

EST3
Carboxylesterase 3

1

5

High-throughput

0.691

High

731865

FAT4
Protocadherin Fat 4

1

13

High-throughput

0.691

High

731868

GALT7
N-acetylgalactosaminyltransferase 7

1

6

High-throughput

0.691

High

731871

FRAS1
Extracellular matrix organizing protein FRAS1

1

20

High-throughput

0.691

High

731885

AGRV1
Adhesion G-protein coupled receptor V1

1

14

High-throughput

0.691

High

731886

HTRA1
Serine protease HTRA1

1

1

High-throughput

0.691

High

731887

PCSK5
Proprotein convertase subtilisin/kexin type 5

1

9

High-throughput

0.691

High

731889

HPLN3
Hyaluronan and proteoglycan link protein 3

1

1

High-throughput

0.691

High

731893

CNTP3
Contactin-associated protein-like 3

1

19

High-throughput

0.691

High

731895

TOR3A
Torsin-3A

1

2

High-throughput

0.691

High

731901

CELR3
Cadherin EGF LAG seven-pass G-type receptor 3

1

13

High-throughput

0.691

High

731839

HYAL2
Hyaluronidase-2

1

0

High-throughput

0.656

High

731904

TXD16
Thioredoxin domain-containing protein 16

1

0

High-throughput

0.656

High

731819

CEAM8
Cell adhesion molecule CEACAM8

1

18

Small-scale

0.647

High

215706

COCH
Cochlin

1

3

High-throughput

0.618

High

731829

NDST1
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1

1

2

High-throughput

0.618

High

731846

MBTP1
Membrane-bound transcription factor site-1 protease

1

1

High-throughput

0.618

High

731860

GLT18
Polypeptide N-acetylgalactosaminyltransferase 18

1

6

High-throughput

0.618

High

731861

TXD11
Thioredoxin domain-containing protein 11

1

13

High-throughput

0.618

High

731870

DYR2
Dihydrofolate reductase 2, mitochondrial

1

1

High-throughput

0.618

High

731875

GLT12
Polypeptide N-acetylgalactosaminyltransferase 12

1

6

High-throughput

0.618

High

539460

ITAM
Integrin alpha-M

1

9

Small-scale

0.618

High

731883

ZPLD1
Zona pellucida-like domain-containing protein 1

2

0

High-throughput

0.602

High

299945

CBPD
Carboxypeptidase D

1

5

High-throughput

0.575

High

731869

CAD24
Cadherin-24

1

4

High-throughput

0.575

High

144045

MA2B1
Lysosomal alpha-mannosidase

1

2

High-throughput

0.536

High

251076

B4GT3
Beta-1,4-galactosyltransferase 3

1

2

High-throughput

0.536

High

337528

LARG1
Xylosyl- and glucuronyltransferase LARGE1

1

2

High-throughput

0.536

High

341288

ECEL1
Endothelin-converting enzyme-like 1

1

1

High-throughput

0.536

High

387379

APOE
Apolipoprotein E

1

1

High-throughput

0.536

High

582373

B4GT1
Beta-1,4-galactosyltransferase 1

1

2

High-throughput

0.536

High

618178

AMD
Peptidyl-glycine alpha-amidating monooxygenase

1

1

High-throughput

0.536

High

649175

GALA
Galanin peptides [Cleaved into: Galanin; Galanin message-associated peptide

1

1

High-throughput

0.536

High

731820

MA1A1
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA

1

3

High-throughput

0.536

High

731821

GALNS
N-acetylgalactosamine-6-sulfatase

1

4

High-throughput

0.536

High

731824

ECE1
Endothelin-converting enzyme 1

1

1

High-throughput

0.536

High

731835

TBA4A
Tubulin alpha-4A chain

1

3

High-throughput

0.536

High

731836

NUCB1
Nucleobindin-1

1

1

High-throughput

0.536

High

731844

DAG1
Dystroglycan 1

1

3

High-throughput

0.536

High

731851

MA2A1
Alpha-mannosidase 2

1

2

High-throughput

0.536

High

731852

LAMA3
Laminin subunit alpha-3

1

15

High-throughput

0.536

High

731853

T132A
Transmembrane protein 132A

1

1

High-throughput

0.536

High

731857

GT253
Inactive glycosyltransferase 25 family member 3

1

2

High-throughput

0.536

High

731874

SULF2
Extracellular sulfatase Sulf-2

1

4

High-throughput

0.536

High

731878

VWDE
von Willebrand factor D and EGF domain-containing protein

1

8

High-throughput

0.536

High

731903

TEN3
Teneurin-3

1

8

High-throughput

0.536

High

731905

DNJB9
DnaJ homolog subfamily B member 9

1

4

High-throughput

0.536

High

731911

LOXL2
Lysyl oxidase homolog 2

1

6

High-throughput

0.536

High

277067

ENTP5
Nucleoside diphosphate phosphatase ENTPD5

1

0

High-throughput

0.513

High

533602

CLUS
Clusterin

1

0

High-throughput

0.513

High

731833

ANAG
Alpha-N-acetylglucosaminidase

1

0

High-throughput

0.513

High

731834

PLTP
Phospholipid transfer protein

1

0

High-throughput

0.513

High

731838

MGT5A
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A

1

0

High-throughput

0.513

High

731896

K1549
UPF0606 protein KIAA1549

1

0

High-throughput

0.513

High

731908

PCYOX
Prenylcysteine oxidase 1

1

0

High-throughput

0.513

High

599972

ZNF16
Zinc finger protein 16

1

0

Small-scale

0.494

High

164730

HS3S1
Heparan sulfate glucosamine 3-O-sulfotransferase 1

1

2

High-throughput

0.489

High

219800

CHSTA
Carbohydrate sulfotransferase 10

1

1

High-throughput

0.489

High

642090

ODBB
2-oxoisovalerate dehydrogenase subunit beta, mitochondrial

1

2

High-throughput

0.489

High

731827

MA2A2
Alpha-mannosidase 2x

1

2

High-throughput

0.489

High

731837

EF1A2
Elongation factor 1-alpha 2

1

3

High-throughput

0.489

High

731847

LTBP1
Latent-transforming growth factor beta-binding protein 1

1

12

High-throughput

0.489

High

731858

MANEL
Glycoprotein endo-alpha-1,2-mannosidase-like protein

1

2

High-throughput

0.489

High

731864

ARSK
Arylsulfatase K

1

4

High-throughput

0.489

High

731866

TMTC3
Protein O-mannosyl-transferase TMTC3

1

3

High-throughput

0.489

High

731872

ERO1B
ERO1-like protein beta

1

1

High-throughput

0.489

High

731876

ELOA2
Elongin-A2

1

1

High-throughput

0.489

High

731877

CA2D3
Voltage-dependent calcium channel subunit alpha-2/delta-3

1

3

High-throughput

0.489

High

731879

LARG2
Xylosyl- and glucuronyltransferase LARGE2

1

1

High-throughput

0.489

High

731880

GUF1
Translation factor GUF1, mitochondrial

1

2

High-throughput

0.489

High

731884

RHBL4
Rhomboid-related protein 4

1

1

High-throughput

0.489

High

731890

TBA1C
Tubulin alpha-1C chain

1

3

High-throughput

0.489

High

731892

EDEM2
ER degradation-enhancing alpha-mannosidase-like protein 2

1

3

High-throughput

0.489

High

731894

EDEM3
ER degradation-enhancing alpha-mannosidase-like protein 3

1

3

High-throughput

0.489

High

731897

CHSTC
Carbohydrate sulfotransferase 12

1

1

High-throughput

0.489

High

731899

EMIL3
EMILIN-3

1

9

High-throughput

0.489

High

731900

TYW1
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1

1

2

High-throughput

0.489

High

731902

UGGG2
UDP-glucose:glycoprotein glucosyltransferase 2

1

4

High-throughput

0.489

High

731909

TM59L
Transmembrane protein 59-like

1

1

High-throughput

0.489

High

337564

FMNL1
Formin-like protein 1

1

2

High-throughput

0.445

High

731826

HSP13
Heat shock 70 kDa protein 13

1

2

High-throughput

0.445

High

183849

VGF
Neurosecretory protein VGF [Cleaved into: Neuroendocrine regulatory peptide-1

1

0

High-throughput

0.426

High

731906

CLIP2
CAP-Gly domain-containing linker protein 2

1

6

High-throughput

0.407

High

91687

PRRT4
Proline-rich transmembrane protein 4

1

0

High-throughput

0.279

Low

731825

NMU
Neuromedin-U [Cleaved into: Neuromedin precursor-related peptide 36

1

0

High-throughput

0.279

Low

731848

NOMO1
BOS complex subunit NOMO1

1

0

High-throughput

0.279

Low

731850

TAZ
Tafazzin

1

0

High-throughput

0.279

Low

731854

OFUT4
GDP-fucose protein O-fucosyltransferase 4

1

0

High-throughput

0.279

Low

731862

GLB1L
Beta-galactosidase-1-like protein

1

0

High-throughput

0.279

Low

731867

CHSS3
Chondroitin sulfate synthase 3

1

0

High-throughput

0.279

Low

731873

P3H3
Prolyl 3-hydroxylase 3

1

0

High-throughput

0.279

Low

731881

PGLT1
Protein O-glucosyltransferase 1

1

0

High-throughput

0.279

Low

731882

KLDC9
Kelch domain-containing protein 9

1

0

High-throughput

0.279

Low

731891

LMF2
Lipase maturation factor 2

1

0

High-throughput

0.279

Low

731898

CHST7
Carbohydrate sulfotransferase 7

1

0

High-throughput

0.279

Low

731907

GAK1A
Golgi-associated kinase 1A

1

0

High-throughput

0.279

Low

731910

MGT4B
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B

1

0

High-throughput

0.279

Low

731859

RPRD2
Regulation of nuclear pre-mRNA domain-containing protein 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025