Protein: HS3S1
Heparan sulfate glucosamine 3-O-sulfotransferase 1 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1) (3-OST-1) (Heparan sulfate 3-O-sulfotransferase 1) (h3-OST-1)

Gene: HS3S1, HS3ST1
Organism: Homo sapiens
Interactions: 37
UniProt ID: O14792

Gene Ontology (top 5):
GO:0005796 - Golgi lumen
GO:0006024 - glycosaminoglycan biosynthetic process
GO:0008146 - sulfotransferase activity
GO:0008467 - [heparan sulfate]-glucosamine 3-sulfotransferase activity
GO:0015012 - heparan sulfate proteoglycan biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

62072

KLRG2
Killer cell lectin-like receptor subfamily G member 2

1

2

High-throughput

0.489

High

164716

B4GT5
Beta-1,4-galactosyltransferase 5

1

1

High-throughput

0.489

High

164717

B4GT4
Beta-1,4-galactosyltransferase 4

1

1

High-throughput

0.489

High

164718

CST8
Cystatin-8

1

1

High-throughput

0.489

High

164720

CRP

1

1

High-throughput

0.489

High

164721

REL1
Prorelaxin H1 [Cleaved into: Relaxin B chain; Relaxin A chain]

1

1

High-throughput

0.489

High

164727

PGFRA
Platelet-derived growth factor receptor alpha

1

2

High-throughput

0.489

High

164728

CMA1
Chymase

1

1

High-throughput

0.489

High

164729

CYTD
Cystatin-D

1

1

High-throughput

0.489

High

164730

CEAM8
Cell adhesion molecule CEACAM8

1

2

High-throughput

0.489

High

164732

LCN6
Epididymal-specific lipocalin-6

1

1

High-throughput

0.489

High

164733

IL5RA
Interleukin-5 receptor subunit alpha

1

1

High-throughput

0.489

High

164738

CEA21
Cell adhesion molecule CEACAM21

1

2

High-throughput

0.489

High

164739

IFNE
Interferon epsilon

1

1

High-throughput

0.489

High

164740

SIA8B
Alpha-2,8-sialyltransferase 8B

1

1

High-throughput

0.489

High

164741

T106A
Transmembrane protein 106A

1

1

High-throughput

0.489

High

164745

CBLN4
Cerebellin-4

1

1

High-throughput

0.489

High

164748

DKKL1
Dickkopf-like protein 1

1

1

High-throughput

0.489

High

164749

CLC11
C-type lectin domain family 11 member A

1

2

High-throughput

0.489

High

164722

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

164736

PGFRL
Platelet-derived growth factor receptor-like protein

1

3

High-throughput

0.470

High

127805

CORT
Cortistatin [Cleaved into: Cortistatin-29; Cortistatin-17]

1

0

High-throughput

0.279

Low

164719

CRLF1
Cytokine receptor-like factor 1

1

0

High-throughput

0.279

Low

164723

FGF4
Fibroblast growth factor 4

1

0

High-throughput

0.279

Low

164724

MMP10
Stromelysin-2

1

0

High-throughput

0.279

Low

164725

BMP4
Bone morphogenetic protein 4

1

0

High-throughput

0.279

Low

164726

PRG2
Bone marrow proteoglycan

1

0

High-throughput

0.279

Low

164731

TNFL8
Tumor necrosis factor ligand superfamily member 8

1

0

High-throughput

0.279

Low

164735

EP3A
Epididymal secretory protein E3-alpha

1

0

High-throughput

0.279

Low

164737

P3H1
Prolyl 3-hydroxylase 1

1

0

High-throughput

0.279

Low

164742

GPX7
Glutathione peroxidase 7

1

0

High-throughput

0.279

Low

164743

CGRE1
Cell growth regulator with EF hand domain protein 1

1

0

High-throughput

0.279

Low

164746

IL20
Interleukin-20

1

0

High-throughput

0.279

Low

164747

DKK3
Dickkopf-related protein 3

1

0

High-throughput

0.279

Low

164750

LIPG
Endothelial lipase

1

0

High-throughput

0.279

Low

164734

DHX9
ATP-dependent RNA helicase A

1

0

Small-scale

0.249

Low

164744

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025