HitPredict

Interactor 1: SYNEM (O15061)
Synemin (Desmuslin)
Gene: SYNM

Interactor 2: FLNC (Q14315)
Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin)
Gene: FLNC

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	25447537
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0042383 - sarcolemma GO:0043034 - costamere
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1565 Hs			1 2725
+	Mm
		57585 SYNEM_MOUSE (1-1555): 0: 1154: 69.14		TITIN_MOUSE (1525-2636): 1.01e-09: 67: 10.72
+	Hs
		166133 SYNEM_HUMAN (1-1565): 0: 1144: 100.00		TITIN_HUMAN (1554-2636): 3.13e-09: 65.5: 10.78
+	Hs
		362721 K1C16_HUMAN (7-336): 6.38e-136: 430: 25.68		FINC_HUMAN (1545-2724): 1.85e-65: 250: 13.83
+	Hs
		362719 K1C19_HUMAN (6-330): 8.56e-134: 421: 23.01		FINC_HUMAN (1545-2724): 1.85e-65: 250: 13.83
+	Hs
		821649 K2C6C_HUMAN (4-325): 4.14e-61: 222: 19.44		ACTN3_HUMAN (23-388): 4.53e-120: 406: 27.63
+	Hs
		362766 K2C5_HUMAN (4-325): 2.24e-60: 220: 18.83		FINC_HUMAN (1545-2724): 1.85e-65: 250: 13.83
+	Hs
		422424 NFM_HUMAN (4-318): 3.87e-17: 89.7: 27.36		SYNE1_HUMAN (33-344): 6.35e-100: 364: 28.65
+	Hs
		362716 VIME_HUMAN (11-320): 2.95e-31: 131: 33.44		FINC_HUMAN (1545-2724): 1.85e-65: 250: 13.83
+	Hs
		363147 KRT81_HUMAN (142-456): 5.36e-12: 72.1: 9.73		FINC_HUMAN (1545-2724): 1.85e-65: 250: 13.83
+	Hs
		363165 K1H1_HUMAN (149-467): 3.74e-10: 65.9: 13.50		FINC_HUMAN (1545-2724): 1.85e-65: 250: 13.83
+	Hs
		422431 NFM_HUMAN (4-318): 3.87e-17: 89.7: 27.36		TITIN_HUMAN (1554-2636): 3.13e-09: 65.5: 10.78