HitPredict

Interactor 1: DCLK1 (O15075)
Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin domain-containing protein 3A) (Doublecortin-like and CAM kinase-like 1) (Doublecortin-like kinase 1)
Gene: DCLK1

Interactor 2: PKHA5 (Q9HAU0)
Pleckstrin homology domain-containing family A member 5 (PH domain-containing family A member 5) (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2)
Gene: PLEKHA5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27173435
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Pkinase
Common GO terms	GO:0014069 - postsynaptic density
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 740 Hs			1 1116
+	Hs
		166574 DCLK1_HUMAN (1-740): 0: 896: 100.00		PKHA7_HUMAN (2-1059): 8.31e-125: 412: 27.32
+	Hs
		166634 DCLK1_HUMAN (1-740): 0: 896: 100.00		GAB2_HUMAN (168-641): 4.97e-48: 185: 12.25
+	Hs
		166601 DCLK1_HUMAN (1-740): 0: 896: 100.00		MAGI1_HUMAN (1-1111): 1.6e-43: 175: 9.66
+	Hs
		166612 DCLK1_HUMAN (1-740): 0: 896: 100.00		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Hs
		208297 DCX_HUMAN (6-345): 2.97e-136: 407: 72.13		PKHA5_HUMAN (1-1116): 0: 609: 100.00
+	Hs
		1334862 KCC2A_HUMAN (387-648): 1.19e-64: 224: 42.48		PKHA5_HUMAN (1-1116): 0: 609: 100.00
+	Hs
		787158 KCC2D_HUMAN (385-737): 1.46e-130: 398: 33.05		RHG25_HUMAN (133-750): 6.67e-56: 208: 14.54
+	Hs
		682077 AKT1_HUMAN (304-706): 2.75e-132: 402: 24.22		GAB2_HUMAN (168-641): 4.97e-48: 185: 12.25
+	Hs
		1167410 M3K3_HUMAN (51-646): 5.47e-139: 424: 18.59		MPRIP_HUMAN (95-395): 8.25e-38: 155: 13.86
+	Hs
		682023 AKT1_HUMAN (304-706): 2.75e-132: 402: 24.22		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Hs
		1039170 KCC2D_HUMAN (385-737): 1.46e-130: 398: 33.05		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Hs
		787157 KCC2G_HUMAN (387-647): 2.94e-63: 223: 43.77		RHG25_HUMAN (133-750): 6.67e-56: 208: 14.54
+	Mm
		515244 KCC2A_MOUSE (387-648): 1.01e-64: 224: 42.48		CNKR2_MOUSE (120-329): 2.5e-47: 186: 26.94
+	Rn
		506782 KCC2A_RAT (387-648): 1.01e-64: 224: 42.48		CNKR2_RAT (120-329): 4.34e-47: 185: 26.48
+	Mm
		659464 KCC2B_MOUSE (387-647): 3.22e-62: 219: 43.77		CNKR2_MOUSE (120-329): 2.5e-47: 186: 26.94
+	Rn
		506741 KCC2A_RAT (387-648): 1.01e-64: 224: 42.48		CAPS1_RAT (70-775): 3.49e-41: 167: 11.16
+	Hs
		1083228 KCC4_HUMAN (386-682): 1.09e-66: 229: 41.14		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Hs
		1039032 KCC2G_HUMAN (387-647): 2.94e-63: 223: 43.77		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85