HitPredict

Interactor 1: CE290 (O15078)
Centrosomal protein of 290 kDa (Cep290) (Bardet-Biedl syndrome 14 protein) (Cancer/testis antigen 87) (CT87) (Nephrocystin-6) (Tumor antigen se2-2)
Gene: CEP290

Interactor 2: CP135 (Q66GS9)
Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4)
Gene: CEP135

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005814 - centriole GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 2479 Hs			1 1140
+	Hs
		1145917 CP250_HUMAN (1-954): 8.71e-29: 129: 9.40		CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00
+	Hs
		1059229 GOGB1_HUMAN (3-911): 1.12e-25: 119: 13.23		CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00
+	Hs
		1068548 PLEC_HUMAN (1-1041): 3.75e-33: 144: 10.85		GRDN_HUMAN (100-1138): 1.23e-43: 176: 11.61
+	Hs
		969580 CENPE_HUMAN (6-1764): 5.52e-58: 225: 11.06		CENPE_HUMAN (557-1139): 7.68e-18: 92.1: 11.35
+	Dm
		1229141 LVA_DROME (1048-2478): 5.15e-37: 156: 9.81		CL190_DROME (1-873): 6e-39: 160: 12.15
+	Hs
		1113839 CP250_HUMAN (1-954): 8.71e-29: 129: 9.40		GRDN_HUMAN (100-1138): 1.23e-43: 176: 11.61
+	Hs
		828575 CENPE_HUMAN (6-1764): 5.52e-58: 225: 11.06		CENPF_HUMAN (101-707): 3.1e-10: 67: 13.08
+	Hs
		502901 MYH3_HUMAN (1092-2146): 4.13e-30: 133: 12.94		MYH6_HUMAN (382-1137): 2.97e-37: 155: 12.55
+	Mm
		93578 PLEC_MOUSE (2-1228): 1.06e-38: 162: 9.59		DESP_MOUSE (212-1059): 2.19e-26: 120: 14.43
+	Hs
		528432 MYH8_HUMAN (1853-2477): 2.16e-24: 115: 9.15		MYH13_HUMAN (1-788): 5.99e-33: 141: 10.29
+	Hs
		522585 MYH7_HUMAN (1748-2477): 7.64e-28: 126: 13.78		MYH7_HUMAN (588-1139): 1.75e-29: 129: 11.94
+	Zm
		5443 A0A1D6DZK4_MAIZE (2-1110): 4e-47: 189: 11.12		A0A1D6DZK4_MAIZE (1-338): 4.22e-09: 63.2: 11.18
+	Hs
		724839 PLEC_HUMAN (1-1041): 3.75e-33: 144: 10.85		MYH9_HUMAN (2-429): 6.32e-14: 79: 11.93
+	Hs
		502933 MYH3_HUMAN (1092-2146): 4.13e-30: 133: 12.94		MYH4_HUMAN (784-1139): 4.49e-17: 89.4: 9.55
+	Hs
		1068652 PLEC_HUMAN (1-1041): 3.75e-33: 144: 10.85		TSG10_HUMAN (187-806): 2.38e-12: 73.2: 14.19
+	Hs
		522657 MYH7_HUMAN (1748-2477): 7.64e-28: 126: 13.78		MYH4_HUMAN (784-1139): 4.49e-17: 89.4: 9.55
+	Hs
		724994 CP250_HUMAN (1-954): 8.71e-29: 129: 9.40		MYH9_HUMAN (2-429): 6.32e-14: 79: 11.93
+	Hs
		528435 MYH8_HUMAN (1853-2477): 2.16e-24: 115: 9.15		MYH4_HUMAN (784-1139): 4.49e-17: 89.4: 9.55
+	Hs
		725073 MACF1_HUMAN (838-2477): 1.87e-20: 102: 9.43		MYH9_HUMAN (2-429): 6.32e-14: 79: 11.93