Protein: TMTC1
Protein O-mannosyl-transferase TMTC1 (EC 2.4.1.109) (Transmembrane O-mannosyltransferase targeting cadherins 1) (Transmembrane and tetratricopeptide repeat-containing 1)

Gene: TMTC1
Organism: Homo sapiens
Interactions: 29
UniProt ID: Q8IUR5

Gene Ontology (top 5):
GO:0000030 - mannosyltransferase activity
GO:0004169 - dolichyl-phosphate-mannose-protein mannosyltransferase activity
GO:0005783 - endoplasmic reticulum
GO:0006396 - RNA processing
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

374732

RASH
GTPase HRas

1

5

High-throughput

0.594

High

1081544

Q0VDC6
peptidylprolyl isomerase

1

10

High-throughput

0.594

High

282602

ERN1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

5

High-throughput

0.515

High

650279

FGFR3
Fibroblast growth factor receptor 3

1

9

High-throughput

0.515

High

843736

HD
Huntingtin

1

2

High-throughput

0.515

High

856786

BAG6
Large proline-rich protein BAG6

1

6

High-throughput

0.515

High

1123967

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

2

High-throughput

0.515

High

1307866

KLK6
Kallikrein-6

1

11

High-throughput

0.515

High

1307870

BACE2
Beta-secretase 2

1

1

High-throughput

0.515

High

1307564

ZDH17
Palmitoyltransferase ZDHHC17

1

11

High-throughput

0.494

High

47368

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.493

High

301535

WFS1
Wolframin

1

0

High-throughput

0.493

High

1307869

CSEN
Calsenilin

1

0

High-throughput

0.493

High

1307867

JPH2
Junctophilin-2

1

2

High-throughput

0.470

High

167311

KLF11
Krueppel-like factor 11

1

7

High-throughput

0.470

High

246024

KIF1B
Kinesin-like protein KIF1B

1

7

High-throughput

0.470

High

361706

F13A
Coagulation factor XIII A chain

1

2

High-throughput

0.470

High

384475

CRYAA
Alpha-crystallin A chain

1

3

High-throughput

0.470

High

415696

HSPB1
Heat shock protein beta-1

1

3

High-throughput

0.470

High

442389

GELS
Gelsolin

1

1

High-throughput

0.470

High

1133895

NMDE3
Glutamate receptor ionotropic, NMDA 2C

1

1

High-throughput

0.470

High

1289858

Q86V38
Atrophin 1

1

8

High-throughput

0.470

High

1307868

NUP58
Nucleoporin p58/p45

1

2

High-throughput

0.470

High

293969

CD123
Translation initiation factor eIF2 assembly protein

1

4

High-throughput

0.437

High

1250608

BCOR
BCL-6 corepressor

1

10

High-throughput

0.437

High

159989

IDLC
Axonemal dynein light intermediate polypeptide 1

1

0

High-throughput

0.268

Low

954527

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.268

Low

1307871

Q9Y649
GW128

1

0

High-throughput

0.268

Low

1271183

DPPA4
Developmental pluripotency-associated protein 4

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025