Protein: UTY
Histone demethylase UTY (EC 1.14.11.68) (Ubiquitously-transcribed TPR protein on the Y chromosome) (Ubiquitously-transcribed Y chromosome tetratricopeptide repeat protein) ([histone H3]-trimethyl-L-lysine(27) demethylase UTY)

Gene: UTY
Organism: Homo sapiens
Interactions: 26
UniProt ID: O14607

Gene Ontology (top 5):
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0005654 - nucleoplasm
GO:0007507 - heart development
GO:0010468 - regulation of gene expression
GO:0031490 - chromatin DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

158679

KMT2D
Histone-lysine N-methyltransferase 2D

1

20

High-throughput

0.691

High

158698

KMT2C
Histone-lysine N-methyltransferase 2C

1

20

High-throughput

0.691

High

158695

NCOA6
Nuclear receptor coactivator 6

2

12

Small-scale

0.618

High

158704

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

2

5

Small-scale

0.611

High

158703

DDX24
ATP-dependent RNA helicase DDX24

1

6

High-throughput

0.553

High

158685

HRG
Histidine-rich glycoprotein

1

3

High-throughput

0.536

High

158690

WDR5
WD repeat-containing protein 5

1

12

High-throughput

0.536

High

158694

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

7

High-throughput

0.536

High

158696

RBBP5
Retinoblastoma-binding protein 5

1

17

High-throughput

0.536

High

158701

PAGR1
PAXIP1-associated glutamate-rich protein 1

1

1

High-throughput

0.536

High

158692

TLE1
Transducin-like enhancer protein 1

1

19

Small-scale

0.527

High

158691

DCD
Dermcidin

1

0

High-throughput

0.513

High

158699

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

9

High-throughput

0.501

High

158693

TLE2
Transducin-like enhancer protein 2

1

17

Small-scale

0.481

High

158684

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

158687

PCNA
Proliferating cell nuclear antigen

1

1

High-throughput

0.479

High

158702

KPCD2
Serine/threonine-protein kinase D2

1

2

High-throughput

0.479

High

158688

PRDX2
Peroxiredoxin-2

1

1

High-throughput

0.439

High

158680

KIF1C
Kinesin-like protein KIF1C

1

10

High-throughput

0.437

High

158681

PRKN
E3 ubiquitin-protein ligase parkin

1

12

High-throughput

0.437

High

158682

CD123
Translation initiation factor eIF2 assembly protein

1

3

High-throughput

0.437

High

158686

MYH3
Myosin-3

1

1

High-throughput

0.437

High

158689

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

1

High-throughput

0.437

High

158697

MEP1B
Meprin A subunit beta

1

2

Small-scale

0.417

High

158683

APOC3
Apolipoprotein C-III

1

0

High-throughput

0.279

Low

158700

SPB12
Serpin B12

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025