HitPredict

Interactor 1: CE290 (O15078)
Centrosomal protein of 290 kDa (Cep290) (Bardet-Biedl syndrome 14 protein) (Cancer/testis antigen 87) (CT87) (Nephrocystin-6) (Tumor antigen se2-2)
Gene: CEP290

Interactor 2: CK5P2 (Q96SN8)
CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215)
Gene: CDK5RAP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35709258
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0005829 - cytosol GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 2479 Hs			1 1893
+	Hs
		1302322 CP250_HUMAN (1-954): 8.71e-29: 129: 9.40		CK5P2_HUMAN (1-1893): 4.16e-171: 572: 100.00
+	Hs
		1034574 GOGA4_HUMAN (1496-2478): 3.53e-35: 150: 10.79		GOGA4_HUMAN (1-1777): 1.29e-60: 233: 10.50
+	Hs
		1034577 GOGA4_HUMAN (1496-2478): 3.53e-35: 150: 10.79		GOGB1_HUMAN (1-1241): 3.09e-44: 180: 9.91
+	Hs
		969580 CENPE_HUMAN (6-1764): 5.52e-58: 225: 11.06		CENPE_HUMAN (1-706): 6.04e-14: 80.3: 12.40
+	Hs
		1059212 GOGB1_HUMAN (3-911): 1.12e-25: 119: 13.23		GOGB1_HUMAN (1-1241): 3.09e-44: 180: 9.91
+	Zm
		5443 A0A1D6DZK4_MAIZE (2-1110): 4e-47: 189: 11.12		A0A1D6DZK4_MAIZE (1238-1875): 6.09e-17: 89.9: 11.56
+	Hs
		724839 PLEC_HUMAN (1-1041): 3.75e-33: 144: 10.85		MYH9_HUMAN (1076-1870): 2.72e-24: 114: 10.17
+	Hs
		1068562 PLEC_HUMAN (1-1041): 3.75e-33: 144: 10.85		MYOME_HUMAN (50-1479): 6.18e-23: 109: 11.47
+	Hs
		724994 CP250_HUMAN (1-954): 8.71e-29: 129: 9.40		MYH9_HUMAN (1076-1870): 2.72e-24: 114: 10.17
+	Hs
		502933 MYH3_HUMAN (1092-2146): 4.13e-30: 133: 12.94		MYH4_HUMAN (1156-1882): 1.02e-19: 99.2: 11.08
+	Hs
		148769 GOGA4_HUMAN (1496-2478): 3.53e-35: 150: 10.79		CTRO_HUMAN (456-1261): 1.07e-13: 79.2: 12.65
+	Hs
		1068617 PLEC_HUMAN (1-1041): 3.75e-33: 144: 10.85		MY18A_HUMAN (124-716): 5.89e-15: 83.4: 16.56
+	Mm
		93578 PLEC_MOUSE (2-1228): 1.06e-38: 162: 9.59		DESP_MOUSE (158-701): 1.83e-09: 65.3: 16.82
+	Hs
		522657 MYH7_HUMAN (1748-2477): 7.64e-28: 126: 13.78		MYH4_HUMAN (1156-1882): 1.02e-19: 99.2: 11.08
+	Hs
		148841 PLEC_HUMAN (1-1041): 3.75e-33: 144: 10.85		CTRO_HUMAN (456-1261): 1.07e-13: 79.2: 12.65
+	Hs
		522585 MYH7_HUMAN (1748-2477): 7.64e-28: 126: 13.78		MYH7_HUMAN (36-501): 1e-15: 86.1: 9.77
+	Hs
		528432 MYH8_HUMAN (1853-2477): 2.16e-24: 115: 9.15		MYH13_HUMAN (50-537): 8.88e-17: 89.3: 13.44
+	Hs
		502901 MYH3_HUMAN (1092-2146): 4.13e-30: 133: 12.94		MYH6_HUMAN (864-1654): 3.35e-11: 71.1: 11.49
+	Rn
		92843 CTRO_RAT (41-893): 1.9e-24: 115: 12.31		ROCK2_RAT (59-667): 3.06e-15: 84.1: 16.29