Interactor 1: IKKA (O15111)
Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK-1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA) (Transcription factor 16) (TCF-16)
Gene: CHUK
Interactor 2: TNAP3 (P21580)
Tumor necrosis factor alpha-induced protein 3 (TNF alpha-induced protein 3) (EC 2.3.2.-) (EC 3.4.19.12) (OTU domain-containing protein 7C) (Putative DNA-binding protein A20) (Zinc finger protein A20) [Cleaved into: A20p50; A20p37]
Gene: TNFAIP3
Species: Homo sapiens
Source: innatedb
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.44 | 0.60 | 0.515 |
The method score is based on:
Property | Details |
---|---|
Experiments | 11594795 |
Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
Interaction Type | physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | - |
Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006954 - inflammatory response GO:0032088 - negative regulation of NF-kappaB transcription factor activity |
Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024