Protein: ZZEF1
Zinc finger ZZ-type and EF-hand domain-containing protein 1

Gene: ZZEF1
Organism: Homo sapiens
Interactions: 136
UniProt ID: O43149

Gene Ontology (top 5):
GO:0005509 - calcium ion binding
GO:0008270 - zinc ion binding
GO:0042393 - histone binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

207863

ODAD4
Outer dynein arm-docking complex subunit 4

2

3

High-throughput

0.726

High

207815

RAPSN
43 kDa receptor-associated protein of the synapse

1

2

High-throughput

0.691

High

207807

DLK1
Protein delta homolog 1

3

1

High-throughput

0.650

High

70882

ZBBX
Zinc finger B-box domain-containing protein 1

2

1

High-throughput

0.628

High

207838

EGFL6
Epidermal growth factor-like protein 6

2

3

High-throughput

0.628

High

207843

CBPA6
Carboxypeptidase A6

2

2

High-throughput

0.628

High

207777

BRD1
Bromodomain-containing protein 1

2

6

High-throughput

0.611

High

207790

YJU2B
Probable splicing factor YJU2B

3

1

High-throughput

0.609

High

207792

FOSL2
Fos-related antigen 2

3

1

High-throughput

0.609

High

207804

CCNG1
Cyclin-G1

3

3

High-throughput

0.609

High

207819

GRPL2
GLIPR1-like protein 2

3

1

High-throughput

0.609

High

207829

MRM1
rRNA methyltransferase 1, mitochondrial

3

1

High-throughput

0.609

High

207834

TM10C
tRNA methyltransferase 10 homolog C

3

1

High-throughput

0.609

High

207874

PAR6B
Partitioning defective 6 homolog beta

3

2

High-throughput

0.609

High

167472

WNT9B
Protein Wnt-9b

3

4

High-throughput

0.599

High

207805

RS4X
Small ribosomal subunit protein eS4, X isoform

3

4

High-throughput

0.599

High

207848

PGLT1
Protein O-glucosyltransferase 1

3

1

High-throughput

0.593

High

178664

ANGP2
Angiopoietin-2

2

1

High-throughput

0.574

High

207775

CLC3A
C-type lectin domain family 3 member A

2

1

High-throughput

0.574

High

207783

GAST
Gastrin [Cleaved into: Gastrin-71

2

1

High-throughput

0.574

High

207785

IPSP
Plasma serine protease inhibitor

2

2

High-throughput

0.574

High

207808

RT34
Small ribosomal subunit protein mS34

2

1

High-throughput

0.574

High

207822

ACBG2
Long-chain-fatty-acid--CoA ligase ACSBG2

2

1

High-throughput

0.574

High

207831

CAVN1
Caveolae-associated protein 1

2

3

High-throughput

0.574

High

207832

LYZL1
Lysozyme-like protein 1

2

3

High-throughput

0.574

High

207835

LYZL2
Lysozyme-like protein 2

2

3

High-throughput

0.574

High

207837

RM10
Large ribosomal subunit protein uL10m

2

1

High-throughput

0.574

High

207841

RBFA
Putative ribosome-binding factor A, mitochondrial

2

1

High-throughput

0.574

High

207859

RT24
Small ribosomal subunit protein uS3m

2

2

High-throughput

0.574

High

207872

CRDL1
Chordin-like protein 1

2

1

High-throughput

0.574

High

207877

WF10A
WAP four-disulfide core domain protein 10A

2

1

High-throughput

0.574

High

207882

CSN7B
COP9 signalosome complex subunit 7b

2

3

High-throughput

0.574

High

207778

TOP3B
DNA topoisomerase 3-beta-1

2

1

High-throughput

0.558

High

207818

RSPO1
R-spondin-1

2

1

High-throughput

0.558

High

207849

SCPDL
Saccharopine dehydrogenase-like oxidoreductase

2

2

High-throughput

0.558

High

207869

GA2L1
GAS2-like protein 1

2

6

High-throughput

0.558

High

207875

RT26
Small ribosomal subunit protein mS26

2

1

High-throughput

0.558

High

207814

CUL3
Cullin-3

1

5

High-throughput

0.553

High

207800

TIMP3
Metalloproteinase inhibitor 3

2

1

High-throughput

0.549

High

207857

PATE1
Prostate and testis expressed protein 1

2

1

High-throughput

0.549

High

207881

GREM2
Gremlin-2

2

1

High-throughput

0.549

High

207883

EMIL3
EMILIN-3

2

2

High-throughput

0.549

High

49554

FEZF1
Fez family zinc finger protein 1

1

16

High-throughput

0.536

High

207839

SULF2
Extracellular sulfatase Sulf-2

1

1

High-throughput

0.536

High

207871

OVOL2
Transcription factor Ovo-like 2

1

11

High-throughput

0.536

High

207894

PA2GD
Group IID secretory phospholipase A2

1

1

High-throughput

0.536

High

207797

PTN4
Tyrosine-protein phosphatase non-receptor type 4

1

2

High-throughput

0.494

High

139036

LAD1
Ladinin-1

1

6

High-throughput

0.489

High

207781

GLUC
Pro-glucagon [Cleaved into: Glicentin; Glicentin-related polypeptide

1

1

High-throughput

0.489

High

207784

DPB1
HLA class II histocompatibility antigen, DP beta 1 chain

1

4

High-throughput

0.489

High

207786

WNT2
Protein Wnt-2

1

4

High-throughput

0.489

High

207787

PGFRB
Platelet-derived growth factor receptor beta

1

1

High-throughput

0.489

High

207789

XRCC5
X-ray repair cross-complementing protein 5

1

2

High-throughput

0.489

High

207791

HGF
Hepatocyte growth factor

1

3

High-throughput

0.489

High

207794

FST
Follistatin

1

1

High-throughput

0.489

High

207795

RS4Y1
Small ribosomal subunit protein eS4, Y isoform 1

1

4

High-throughput

0.489

High

207798

CNR2
Cannabinoid receptor 2

1

2

Small-scale

0.489

High

207809

RT09
Small ribosomal subunit protein uS9m

1

2

High-throughput

0.489

High

207816

IL27B
Interleukin-27 subunit beta

1

4

High-throughput

0.489

High

207828

ISK14
Serine protease inhibitor Kazal-type 14

1

1

High-throughput

0.489

High

207830

PRR27
Proline-rich protein 27

1

4

High-throughput

0.489

High

207842

FGRL1
Fibroblast growth factor receptor-like 1

1

3

High-throughput

0.489

High

207844

NKAP
NF-kappa-B-activating protein

1

2

High-throughput

0.489

High

207846

LRC17
Leucine-rich repeat-containing protein 17

1

1

High-throughput

0.489

High

207850

PRS33
Serine protease 33

1

1

High-throughput

0.489

High

207851

GP156
Probable G-protein coupled receptor 156

1

1

High-throughput

0.489

High

207852

G45IP
Large ribosomal subunit protein mL64

1

1

High-throughput

0.489

High

207853

FA81A
Protein FAM81A

1

1

High-throughput

0.489

High

207854

RM30
Large ribosomal subunit protein uL30m

1

2

High-throughput

0.489

High

207856

HASP
Serine/threonine-protein kinase haspin

1

1

High-throughput

0.489

High

207865

TEFM
Transcription elongation factor, mitochondrial

1

1

High-throughput

0.489

High

207870

SEM3C
Semaphorin-3C

1

1

High-throughput

0.489

High

207887

GABR1
Gamma-aminobutyric acid type B receptor subunit 1

1

1

High-throughput

0.489

High

207888

DKK2
Dickkopf-related protein 2

1

1

High-throughput

0.489

High

207891

MRM2
rRNA methyltransferase 2, mitochondrial

1

1

High-throughput

0.489

High

207895

RT07
Small ribosomal subunit protein uS7m

1

2

High-throughput

0.489

High

156713

CTRO
Citron Rho-interacting kinase

1

2

High-throughput

0.479

High

207773

PRKN
E3 ubiquitin-protein ligase parkin

1

5

High-throughput

0.479

High

207796

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.479

High

207826

RN123
E3 ubiquitin-protein ligase RNF123

1

5

High-throughput

0.479

High

207833

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.479

High

207890

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

207825

MYOME
Myomegalin

1

8

High-throughput

0.470

High

207803

MMP14
Matrix metalloproteinase-14

1

3

High-throughput

0.445

High

169828

AURKA
Aurora kinase A

1

5

High-throughput

0.437

High

207771

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.437

High

207772

PRC1
Protein regulator of cytokinesis 1

1

1

High-throughput

0.437

High

207793

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

207799

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

207801

RL3
Large ribosomal subunit protein uL3

1

2

High-throughput

0.437

High

207806

H31
Histone H3.1

1

7

High-throughput

0.437

High

207810

H33
Histone H3.3

1

7

High-throughput

0.437

High

207811

VAC14
Protein VAC14 homolog

1

5

High-throughput

0.437

High

207861

AURKB
Aurora kinase B

1

5

High-throughput

0.437

High

207864

YI001
Uncharacterized protein FLJ30774

1

1

High-throughput

0.437

High

207879

GAN
Gigaxonin

1

3

High-throughput

0.437

High

207880

PKHA4
Pleckstrin homology domain-containing family A member 4

1

7

High-throughput

0.437

High

207892

XPO7
Exportin-7

1

2

High-throughput

0.437

High

95873

E7EPC3
Protein Wnt

1

4

High-throughput

0.407

High

133829

FOXN3
Forkhead box protein N3

1

1

High-throughput

0.407

High

207780

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.407

High

207813

BFSP2
Phakinin

1

8

High-throughput

0.407

High

207820

CTL4
Choline transporter-like protein 4

1

1

High-throughput

0.407

High

207824

DIK1A
Divergent protein kinase domain 1A

1

1

High-throughput

0.407

High

207827

A16L1
Autophagy-related protein 16-1

1

3

High-throughput

0.407

High

207836

RIC3
Protein RIC-3

1

2

High-throughput

0.407

High

207847

CI163
Uncharacterized protein C9orf163

1

1

High-throughput

0.407

High

207855

HUMMR
Protein MGARP

1

1

High-throughput

0.407

High

207862

MF14A
Hippocampus abundant transcript 1 protein

1

2

High-throughput

0.407

High

207873

S4A5
Electrogenic sodium bicarbonate cotransporter 4

1

1

High-throughput

0.407

High

207893

FZD10
Frizzled-10

1

2

High-throughput

0.407

High

207896

ZDHC9
Palmitoyltransferase ZDHHC9

1

3

High-throughput

0.407

High

207812

HSPB3
Heat shock protein beta-3

1

0

High-throughput

0.282

High

207858

PHYIP
Phytanoyl-CoA hydroxylase-interacting protein

1

0

High-throughput

0.282

High

207774

GEMI
Geminin

1

0

High-throughput

0.279

Low

207782

IGF2
Insulin-like growth factor 2

1

0

High-throughput

0.279

Low

207817

ICAM4
Intercellular adhesion molecule 4

1

0

High-throughput

0.279

Low

207823

DCA12
DDB1- and CUL4-associated factor 12

1

0

High-throughput

0.279

Low

207840

D107A
Beta-defensin 107

1

0

High-throughput

0.279

Low

207845

DB125
Beta-defensin 125

1

0

High-throughput

0.279

Low

207860

THOC1
THO complex subunit 1

1

0

High-throughput

0.279

Low

207866

TGS1
Trimethylguanosine synthase

1

0

High-throughput

0.279

Low

207867

CK5P1
Mitochondrial tRNA methylthiotransferase CDK5RAP1

1

0

High-throughput

0.279

Low

207868

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.279

Low

207876

CHST5
Carbohydrate sulfotransferase 5

1

0

High-throughput

0.279

Low

207878

IL25
Interleukin-25

1

0

High-throughput

0.279

Low

207884

ABHDA
Palmitoyl-protein thioesterase ABHD10, mitochondrial

1

0

High-throughput

0.279

Low

207885

RM27
Large ribosomal subunit protein bL27m

1

0

High-throughput

0.279

Low

207889

CGBP1
CGG triplet repeat-binding protein 1

1

0

High-throughput

0.279

Low

207788

SKIL
Ski-like protein

1

0

High-throughput

0.265

Low

104689

F6VUV4
Dehydrogenase/reductase 4 like 2

1

0

High-throughput

0.249

Low

207776

MFN2
Mitofusin-2

1

0

High-throughput

0.249

Low

207779

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

207821

TM41B
Transmembrane protein 41B

1

0

High-throughput

0.249

Low

207886

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.249

Low

207802

5HT3A
5-hydroxytryptamine receptor 3A

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025