Protein: 3BP2
SH3 domain-binding protein 2 (3BP-2)

Gene: 3BP2, SH3BP2
Organism: Homo sapiens
Interactions: 46
UniProt ID: P78314

Gene Ontology (top 5):
GO:0001784 - phosphotyrosine residue binding
GO:0007165 - signal transduction
GO:0017124 - SH3 domain binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

548682

VAV
Proto-oncogene vav

4

10

Small-scale

0.918

High

940672

SH3K1
SH3 domain-containing kinase-binding protein 1

2

15

Small-scale

0.832

High

796543

KSYK
Tyrosine-protein kinase SYK

3

20

Small-scale

0.821

High

940678

DBNL
Drebrin-like protein

3

17

Small-scale

0.788

High

855783

VAV2
Guanine nucleotide exchange factor VAV2

2

11

Small-scale

0.786

High

536576

HCLS1
Hematopoietic lineage cell-specific protein

2

20

High-throughput

0.783

High

940667

SRC8
Src substrate cortactin

2

19

High-throughput

0.783

High

49634

RHG10
Rho GTPase-activating protein 10

2

2

High-throughput

0.767

High

580976

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

3

1

Small-scale

0.763

High

796467

ZAP70
Tyrosine-protein kinase ZAP-70

1

19

Small-scale

0.724

High

117895

MYO1F
Unconventional myosin-If

2

4

High-throughput

0.700

High

441480

MET
Hepatocyte growth factor receptor

1

7

High-throughput

0.692

High

499255

KIT
Mast/stem cell growth factor receptor Kit

1

3

High-throughput

0.692

High

337423

ABL1
Tyrosine-protein kinase ABL1

1

15

High-throughput

0.647

High

383735

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

11

High-throughput

0.647

High

601888

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

13

High-throughput

0.647

High

924462

GRB2
Growth factor receptor-bound protein 2

1

20

Small-scale

0.647

High

940669

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

15

High-throughput

0.647

High

776643

STAT3
Signal transducer and activator of transcription 3

1

1

High-throughput

0.621

High

522898

SRC
Proto-oncogene tyrosine-protein kinase Src

1

15

Small-scale

0.618

High

610349

CBL
E3 ubiquitin-protein ligase CBL

2

4

Small-scale

0.595

High

665856

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

0

Small-scale

0.593

High

940674

TNKS2
Poly [ADP-ribose] polymerase tankyrase-2

2

5

Small-scale

0.593

High

646789

1433T
14-3-3 protein theta

1

20

Small-scale

0.581

High

411669

LCK
Tyrosine-protein kinase Lck

1

15

Small-scale

0.575

High

562639

PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

1

1

Small-scale

0.575

High

412125

FYN
Tyrosine-protein kinase Fyn

1

15

Small-scale

0.555

High

507946

FGFR1
Fibroblast growth factor receptor 1

1

3

Small-scale

0.555

High

940670

SH3R1
E3 ubiquitin-protein ligase SH3RF1

1

16

High-throughput

0.555

High

940679

VAV3
Guanine nucleotide exchange factor VAV3

1

12

Small-scale

0.553

High

207441

LAT
Linker for activation of T-cells family member 1

2

1

Small-scale

0.543

High

940676

PDLI7
PDZ and LIM domain protein 7

1

3

High-throughput

0.494

High

940673

CD244
Natural killer cell receptor 2B4

1

3

Small-scale

0.457

High

886392

NAL12
NACHT, LRR and PYD domains-containing protein 12

1

0

Small-scale

0.438

High

255676

OBSL1
Obscurin-like protein 1

1

9

High-throughput

0.437

High

310046

TNKS1
Poly [ADP-ribose] polymerase tankyrase-1

1

5

Small-scale

0.437

High

600124

TAF1
Transcription initiation factor TFIID subunit 1

1

2

High-throughput

0.437

High

617280

SP100
Nuclear autoantigen Sp-100

1

5

High-throughput

0.437

High

631397

BRD2
Bromodomain-containing protein 2

1

3

High-throughput

0.437

High

940668

CUL7
Cullin-7

1

2

High-throughput

0.437

High

940675

SP110
Sp110 nuclear body protein

1

5

High-throughput

0.437

High

162620

XPO1
Exportin-1

1

0

High-throughput

0.249

Low

940666

IKZF1
DNA-binding protein Ikaros

1

0

Small-scale

0.249

Low

940677

RN146
E3 ubiquitin-protein ligase RNF146

1

0

Small-scale

0.249

Low

364545

TRFE
Serotransferrin

1

0

High-throughput

0.238

Low

940671

HAVR2
Hepatitis A virus cellular receptor 2

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024