HitPredict

Interactor 1: LSM1 (O15116)
U6 snRNA-associated Sm-like protein LSm1 (Cancer-associated Sm-like) (Small nuclear ribonuclear CaSm)
Gene: LSM1

Interactor 2: LSM3 (P62310)
U6 snRNA-associated Sm-like protein LSm3
Gene: LSM3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.94	1.00	0.971

Property	Details
Experiments	25416956, 26871637, 29395067, 15231747, 32296183, 33961781, unassigned1304
Identification Methods	two hybrid, proximity labelling technology, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0000932 - P-body GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0006397 - mRNA processing and 1 others more... GO:1990726 - Lsm1-7-Pat1 complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 133 Hs			1 102
+	Mm
		912216 LSM1_MOUSE (1-133): 1.13e-53: 166: 97.74		LSM3_MOUSE (1-102): 8.88e-41: 131: 100.00
+	Hs
		167663 LSM1_HUMAN (1-133): 3.57e-53: 165: 100.00		RSMB_HUMAN (23-102): 1.47e-24: 94.3: 23.81
+	Hs
		167683 LSM1_HUMAN (1-133): 3.57e-53: 165: 100.00		SMD2_HUMAN (13-95): 9.24e-26: 94.3: 29.07
+	Hs
		167727 LSM1_HUMAN (1-133): 3.57e-53: 165: 100.00		LSM5_HUMAN (17-91): 2.3e-25: 92.4: 34.67
+	Hs
		321387 LSM8_HUMAN (7-95): 2.25e-31: 108: 33.33		LSM3_HUMAN (1-102): 8.88e-41: 131: 100.00
+	Mm
		912214 LSM8_MOUSE (7-95): 2.25e-31: 108: 33.33		LSM3_MOUSE (1-102): 8.88e-41: 131: 100.00
+	Dm
		1213200 Q9W087_DROME (8-97): 1.7e-31: 109: 26.37		Q8IMX8_DROME (1-102): 1.58e-37: 123: 76.70
+	Hs
		167725 LSM1_HUMAN (1-133): 3.57e-53: 165: 100.00		LSM7_HUMAN (1-97): 3.84e-15: 66.6: 23.71
+	Hs
		912202 LSM7_HUMAN (8-89): 4.34e-27: 98.5: 29.89		LSM3_HUMAN (1-102): 8.88e-41: 131: 100.00
+	Dm
		1373283 Q9W2K2_DROME (1-124): 3.53e-39: 130: 63.71		Q9VRT7_DROME (17-90): 8.53e-25: 90.8: 33.78
+	Sc
		810530 LSM1_YEAST (4-123): 5.07e-34: 118: 40.98		LSM3_YEAST (14-98): 4.21e-24: 88.9: 41.18
+	Dm
		1367660 Q9W087_DROME (8-97): 1.7e-31: 109: 26.37		SMD2_DROME (13-95): 3.12e-27: 97.8: 30.23
+	Hs
		321392 LSM8_HUMAN (7-95): 2.25e-31: 108: 33.33		RSMN_HUMAN (23-102): 3e-25: 96.2: 23.81
+	Hs
		321370 LSM8_HUMAN (7-95): 2.25e-31: 108: 33.33		RSMB_HUMAN (23-102): 1.47e-24: 94.3: 23.81
+	Hs
		321443 LSM8_HUMAN (7-95): 2.25e-31: 108: 33.33		LSM5_HUMAN (17-91): 2.3e-25: 92.4: 34.67
+	At
		1228013 LSM1B_ARATH (7-118): 1.52e-37: 125: 48.21		LSM7_ARATH (15-97): 6.18e-16: 68.5: 31.33
+	Hs
		539178 LSM7_HUMAN (8-89): 4.34e-27: 98.5: 29.89		RSMB_HUMAN (23-102): 1.47e-24: 94.3: 23.81
+	Hs
		912587 LSM7_HUMAN (8-89): 4.34e-27: 98.5: 29.89		SMD2_HUMAN (13-95): 9.24e-26: 94.3: 29.07
+	Sc
		768230 LSM1_YEAST (4-123): 5.07e-34: 118: 40.98		LSM5_YEAST (17-97): 3.11e-18: 74.3: 23.46
+	Hs
		321438 LSM8_HUMAN (7-95): 2.25e-31: 108: 33.33		LSM7_HUMAN (1-97): 3.84e-15: 66.6: 23.71