Interactor 1: IKKB (O14920)
Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK-2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) (Serine/threonine protein kinase IKBKB) (EC 2.7.11.1)
Gene: IKBKB

Interactor 2: SASH1 (O94885)
SAM and SH3 domain-containing protein 1 (Proline-glutamate repeat-containing protein)
Gene: SASH1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.757

The method score is based on:

Property Details
Experiments 30480076, 23776175
Identification Methods two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~SAM_1
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0019901 - protein kinase binding
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 756
Hs

1 1247
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025