HitPredict

Interactor 1: RPAC1 (O15160)
DNA-directed RNA polymerases I and III subunit RPAC1 (DNA-directed RNA polymerase I subunit C) (RNA polymerases I and III subunit AC1) (AC40) (DNA-directed RNA polymerases I and III 40 kDa polypeptide) (RPA40) (RPA39) (RPC40)
Gene: POLR1C

Interactor 2: RPA1 (O95602)
DNA-directed RNA polymerase I subunit RPA1 (RNA polymerase I subunit A1) (EC 2.7.7.6) (A190) (DNA-directed RNA polymerase I largest subunit) (DNA-directed RNA polymerase I subunit A) (RNA polymerase I 194 kDa subunit) (RPA194)
Gene: POLR1A

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.968

The method score is based on:

Property Details
Experiments 28514442, 33961781, 35271311, 26496610, 24981860, 36271492, 19214185
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, chromatography technology
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_L~RNA_pol_Rpb1_2, RNA_pol_L~RNA_pol_Rpb1_3, RNA_pol_L~RNA_pol_Rpb1_4, RNA_pol_L~RNA_pol_Rpb1_5
Common GO terms GO:0001054 - RNA polymerase I activity
GO:0003677 - DNA binding
GO:0003899 - DNA-directed 5'-3' RNA polymerase activity
GO:0005654 - nucleoplasm
GO:0005736 - RNA polymerase I complex
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 346
Hs

1 1720
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Last updated: 15 Jul 2024