HitPredict

Interactor 1: TIF1A (O15164)
Transcription intermediary factor 1-alpha (TIF1-alpha) (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM24) (RING finger protein 82) (RING-type E3 ubiquitin transferase TIF1-alpha) (Tripartite motif-containing protein 24)
Gene: TRIM24

Interactor 2: SSRP1 (Q08945)
FACT complex subunit SSRP1 (Chromatin-specific transcription elongation factor 80 kDa subunit) (Facilitates chromatin transcription complex 80 kDa subunit) (FACT 80 kDa subunit) (FACTp80) (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (hSSRP1) (T160)
Gene: SSRP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	30479348, 31753913, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1050 Hs			1 709
+	Hs
		996961 TRI33_HUMAN (53-1045): 1.19e-149: 477: 46.27		SSRP1_HUMAN (1-709): 0: 805: 100.00
+	Hs
		170476 TIF1A_HUMAN (1-1050): 0: 590: 100.00		SOX17_HUMAN (475-708): 1.45e-32: 132: 12.61
+	Hs
		170279 TIF1A_HUMAN (1-1050): 0: 590: 100.00		SOX5_HUMAN (441-648): 2.62e-30: 129: 19.23
+	Hs
		170296 TIF1A_HUMAN (1-1050): 0: 590: 100.00		SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31
+	Hs
		1332331 TRI33_HUMAN (53-1045): 1.19e-149: 477: 46.27		SOX17_HUMAN (475-708): 1.45e-32: 132: 12.61
+	Hs
		818613 TRI33_HUMAN (53-1045): 1.19e-149: 477: 46.27		SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31
+	Hs
		617392 TRI33_HUMAN (53-1045): 1.19e-149: 477: 46.27		SP100_HUMAN (486-629): 1.52e-24: 111: 28.86
+	Hs
		175726 TRI18_HUMAN (47-471): 7.24e-73: 257: 15.35		HM20B_HUMAN (508-709): 6.25e-36: 139: 18.81
+	Hs
		1270803 CBP_HUMAN (386-1001): 1.83e-61: 232: 15.56		HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20
+	Hs
		585039 RO52_HUMAN (114-485): 2.09e-64: 227: 12.67		CIC_HUMAN (424-708): 7.87e-39: 157: 16.49
+	Rn
		94293 F1M9G7_RAT (441-1001): 1.56e-65: 245: 18.02		SOX9_RAT (447-703): 1.01e-33: 137: 14.77
+	Hs
		1223389 TRI22_HUMAN (122-481): 1.35e-62: 223: 12.12		CIC_HUMAN (424-708): 7.87e-39: 157: 16.49
+	Hs
		818828 CBP_HUMAN (386-1001): 1.83e-61: 232: 15.56		SOX9_HUMAN (447-703): 1.35e-34: 140: 15.15
+	Mm
		57642 EP300_MOUSE (376-1001): 3.38e-64: 240: 15.94		A2AWT7_MOUSE (355-708): 5.83e-25: 112: 10.61
+	Hs
		668542 PML_HUMAN (23-555): 2.49e-55: 209: 18.15		PMS1_HUMAN (400-704): 7.54e-34: 141: 16.23
+	Hs
		617349 CBP_HUMAN (386-1001): 1.83e-61: 232: 15.56		SP100_HUMAN (486-629): 1.52e-24: 111: 28.86
+	Hs
		818410 TRI56_HUMAN (42-615): 2.82e-57: 214: 15.29		SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31
+	Hs
		617248 PML_HUMAN (23-555): 2.49e-55: 209: 18.15		SP100_HUMAN (486-629): 1.52e-24: 111: 28.86
+	Hs
		643378 CBP_HUMAN (386-1001): 1.83e-61: 232: 15.56		HMGB2_HUMAN (540-698): 5.17e-15: 76.3: 23.53
+	Hs
		449782 CBP_HUMAN (386-1001): 1.83e-61: 232: 15.56		HMGB1_HUMAN (543-634): 1e-14: 75.5: 34.04