HitPredict

Interactor 1: LRAD4 (O15165)
Low-density lipoprotein receptor class A domain-containing protein 4
Gene: LDLRAD4

Interactor 2: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 306 Hs			1 504
+	Hs
		125004 LRAD4_HUMAN (1-306): 0: 578: 100.00		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Hs
		170560 LRAD4_HUMAN (1-306): 0: 578: 100.00		ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17
+	Hs
		170561 LRAD4_HUMAN (1-306): 0: 578: 100.00		NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73
+	Hs
		170569 LRAD4_HUMAN (1-306): 0: 578: 100.00		SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05
+	Hs
		170566 LRAD4_HUMAN (1-306): 0: 578: 100.00		WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42
+	Hs
		170532 LRAD4_HUMAN (1-306): 0: 578: 100.00		NEDD4_HUMAN (40-504): 2.15e-103: 338: 19.26
+	Hs
		170568 LRAD4_HUMAN (1-306): 0: 578: 100.00		SMUF2_HUMAN (99-504): 4.95e-107: 337: 19.19
+	Hs
		1282578 PMEPA_HUMAN (57-304): 1.13e-133: 382: 66.14		NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73
+	Hs
		170543 LRAD4_HUMAN (1-306): 0: 578: 100.00		MAGI3_HUMAN (69-270): 5.85e-40: 156: 21.64
+	Hs
		170562 LRAD4_HUMAN (1-306): 0: 578: 100.00		MAGI1_HUMAN (69-305): 1.87e-39: 155: 18.32
+	Hs
		170544 LRAD4_HUMAN (1-306): 0: 578: 100.00		WWC2_HUMAN (163-315): 3.48e-35: 142: 24.18
+	Hs
		808211 PMEPA_HUMAN (57-304): 1.13e-133: 382: 66.14		NEDD4_HUMAN (40-504): 2.15e-103: 338: 19.26
+	Mm
		57497 A2APF4_MOUSE (56-302): 2.79e-124: 358: 64.54		NEDD4_MOUSE (28-504): 2.4e-113: 357: 16.98
+	Mm
		808374 PMEPA_MOUSE (56-302): 1.19e-122: 353: 64.54		NEDD4_MOUSE (28-504): 2.4e-113: 357: 16.98
+	Hs
		170571 LRAD4_HUMAN (1-306): 0: 578: 100.00		WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61
+	Hs
		170549 LRAD4_HUMAN (1-306): 0: 578: 100.00		HECW1_HUMAN (2-222): 1.33e-24: 110: 14.96
+	Hs
		170573 LRAD4_HUMAN (1-306): 0: 578: 100.00		HECW2_HUMAN (13-303): 1.56e-14: 79: 14.79