Interactor 1: LRAD4 (O15165)
Low-density lipoprotein receptor class A domain-containing protein 4
Gene: LDLRAD4

Interactor 2: SMUF1 (Q9HCE7)
E3 ubiquitin-protein ligase SMURF1 (hSMURF1) (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase SMURF1) (SMAD ubiquitination regulatory factor 1) (SMAD-specific E3 ubiquitin-protein ligase 1)
Gene: SMURF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 0.60 0.667

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0030512 - negative regulation of transforming growth factor beta receptor signaling pathway
GO:0070412 - R-SMAD binding
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 306
Hs

1 757
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024