Protein: EXT1
Exostosin-1 (EC 2.4.1.225) (Exostosin glycosyltransferase 1) (Heparan sulfate co-polymerase subunit EXT1) (Multiple exostoses protein 1) (N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase)

Gene: EXT1
Organism: Homo sapiens
Interactions: 81
UniProt ID: Q16394

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0000271 - polysaccharide biosynthetic process
GO:0001503 - ossification
GO:0001958 - endochondral ossification
GO:0001974 - blood vessel remodeling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1157384

EXT2
Exostosin-2

4

12

Small-scale

0.892

High

230792

EXTL3
Exostosin-like 3

1

12

High-throughput

0.691

High

1157397

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

3

1

High-throughput

0.667

High

1042625

UPAR
Urokinase plasminogen activator surface receptor

3

0

High-throughput

0.638

High

1157359

MPPE1
Metallophosphoesterase 1

2

2

High-throughput

0.628

High

1157364

S39A5
Zinc transporter ZIP5

2

12

High-throughput

0.628

High

1157356

EXT1
Exostosin-1

1

12

Small-scale

0.618

High

1116208

PTC1
Protein patched homolog 1

3

1

High-throughput

0.609

High

1157373

SYNE4
Nesprin-4

3

1

High-throughput

0.609

High

219305

B4GA1
Beta-1,4-glucuronyltransferase 1

2

0

High-throughput

0.602

High

1157369

LRC33
Transforming growth factor beta activator LRRC33

2

0

High-throughput

0.602

High

1157376

TOIP2
Torsin-1A-interacting protein 2

3

0

High-throughput

0.585

High

519616

LYAG
Lysosomal alpha-glucosidase

2

1

High-throughput

0.574

High

1101337

SG2A2
Mammaglobin-A

2

4

High-throughput

0.574

High

1157394

GLP3L
Golgi phosphoprotein 3-like

1

4

Small-scale

0.561

High

1157395

GOLP3
Golgi phosphoprotein 3

1

4

Small-scale

0.561

High

1157380

CA054
Uncharacterized protein C1orf54

2

3

High-throughput

0.549

High

857465

NOTC1
Neurogenic locus notch homolog protein 1

1

2

High-throughput

0.541

High

173931

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

3

High-throughput

0.536

High

380431

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

1

7

High-throughput

0.536

High

593381

PGFRA
Platelet-derived growth factor receptor alpha

1

2

High-throughput

0.536

High

607929

ACHB2
Neuronal acetylcholine receptor subunit beta-2

1

5

High-throughput

0.536

High

1157367

GLT10
Polypeptide N-acetylgalactosaminyltransferase 10

1

2

High-throughput

0.536

High

1157385

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

3

High-throughput

0.536

High

1157383

OSTF1
Osteoclast-stimulating factor 1

1

2

High-throughput

0.515

High

1053185

ZP2
Zona pellucida sperm-binding protein 2

1

0

High-throughput

0.513

High

1157358

ASTRB
Protein Aster-B

1

0

High-throughput

0.513

High

1157390

TMM59
Transmembrane protein 59

1

0

High-throughput

0.513

High

1157392

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.513

High

286543

SG2A1
Mammaglobin-B

1

4

High-throughput

0.489

High

469487

SYPH
Synaptophysin

1

1

High-throughput

0.489

High

518848

CCL3
C-C motif chemokine 3

1

2

High-throughput

0.489

High

821718

CD79B
B-cell antigen receptor complex-associated protein beta chain

1

1

High-throughput

0.489

High

1157357

CL12B
C-type lectin domain family 12 member B

1

5

High-throughput

0.489

High

1157372

NRSN1
Neurensin-1

1

1

High-throughput

0.489

High

1157389

LCFC1
Sperm-egg fusion protein LLCFC1

1

1

High-throughput

0.489

High

1157391

TMPSD
Transmembrane protease serine 13

1

4

High-throughput

0.489

High

1090410

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

1

Small-scale

0.481

High

218226

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.479

High

686750

CNTF
Ciliary neurotrophic factor

1

1

High-throughput

0.470

High

1140332

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

170774

CLGN
Calmegin

1

3

High-throughput

0.445

High

380291

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

7

High-throughput

0.445

High

1098404

DNJC3
DnaJ homolog subfamily C member 3

1

2

High-throughput

0.445

High

1154979

ADIPO
Adiponectin

1

2

High-throughput

0.445

High

1157368

OSTA
Organic solute transporter subunit alpha

1

2

High-throughput

0.445

High

1157374

WDTC1
WD and tetratricopeptide repeats protein 1

1

2

High-throughput

0.445

High

1157375

ZNT7
Zinc transporter 7

1

9

High-throughput

0.445

High

1157378

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

9

High-throughput

0.445

High

1157382

S39A7
Zinc transporter SLC39A7

1

12

High-throughput

0.445

High

293749

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.437

High

1157396

TFR2
Transferrin receptor protein 2

1

1

High-throughput

0.437

High

465963

CO1A2
Collagen alpha-2(I) chain

1

0

High-throughput

0.426

High

566688

PDIA4
Protein disulfide-isomerase A4

1

0

High-throughput

0.426

High

1157366

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

1

0

High-throughput

0.426

High

73808

C1T9B
Complement C1q and tumor necrosis factor-related protein 9B

1

2

High-throughput

0.407

High

95945

E7ET36
Transferrin receptor 2

1

1

High-throughput

0.407

High

479056

CEL3A
Chymotrypsin-like elastase family member 3A

1

5

High-throughput

0.407

High

505827

C1T9A
Complement C1q and tumor necrosis factor-related protein 9A

1

2

High-throughput

0.407

High

976806

LCN6
Epididymal-specific lipocalin-6

1

1

High-throughput

0.407

High

1135652

MF13A
Transmembrane protein 180

1

1

High-throughput

0.407

High

1139434

S39AE
Metal cation symporter ZIP14

1

12

High-throughput

0.407

High

1157360

DCAF6
DDB1- and CUL4-associated factor 6

1

2

High-throughput

0.407

High

1157362

DCAF8
DDB1- and CUL4-associated factor 8

1

3

High-throughput

0.407

High

1157363

MFSD5
Molybdate-anion transporter

1

3

High-throughput

0.407

High

1157370

UBR2
E3 ubiquitin-protein ligase UBR2

1

1

High-throughput

0.407

High

1157371

S15A3
Solute carrier family 15 member 3

1

1

High-throughput

0.407

High

1157387

T106A
Transmembrane protein 106A

1

3

High-throughput

0.407

High

1157388

SAAL1
Protein SAAL1

1

1

High-throughput

0.407

High

828369

PEX19
Peroxisomal biogenesis factor 19

3

0

High-throughput

0.347

High

1034733

NAAA
N-acylethanolamine-hydrolyzing acid amidase

3

0

High-throughput

0.347

High

388530

CRP

2

0

High-throughput

0.328

High

1157393

IFG15
Torsin-1A-interacting protein 2, isoform IFRG15

2

0

High-throughput

0.305

High

1157386

FBXW7
F-box/WD repeat-containing protein 7

1

0

High-throughput

0.282

High

1157361

NHLC3
NHL repeat-containing protein 3

1

0

High-throughput

0.279

Low

1157365

LRC55
Leucine-rich repeat-containing protein 55

1

0

High-throughput

0.279

Low

1157379

SG1C1
Secretoglobin family 1C member 1

1

0

High-throughput

0.279

Low

556853

MYH1
Myosin-1

1

0

High-throughput

0.249

Low

1157377

CDC26
Anaphase-promoting complex subunit CDC26

1

0

High-throughput

0.232

Low

1157381

PATE1
Prostate and testis expressed protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025