Interactor 1: AXIN1 (O15169)
Axin-1 (Axis inhibition protein 1) (hAxin)
Gene: AXIN1

Interactor 2: AXIN1 (O15169)
Axin-1 (Axis inhibition protein 1) (hAxin)
Gene: AXIN1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.948

The method score is based on:

Property Details
Experiments 16169070, 11884395, 18632848, 21245303, 23892894, 10811618
Identification Methods two hybrid, affinity chromatography technology, nuclear magnetic resonance, molecular sieving, light scattering, anti tag coimmunoprecipitation, x-ray crystallography, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DIX~DIX, RGS~RGS
Common GO terms GO:0000209 - protein polyubiquitination
GO:0001701 - in utero embryonic development
GO:0001934 - positive regulation of protein phosphorylation
GO:0002039 - p53 binding
GO:0005634 - nucleus
and 51 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 862
Hs

1 862
+ Mm
+ Rn
+ Hs
+ Mm
+ Hs
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024