Protein: SEM6B
Semaphorin-6B (Semaphorin-Z) (Sema Z)

Gene: SEM6B, SEMA6B
Organism: Homo sapiens
Interactions: 46
UniProt ID: Q9H3T3

Gene Ontology (top 5):
GO:0001755 - neural crest cell migration
GO:0005886 - plasma membrane
GO:0007411 - axon guidance
GO:0007417 - central nervous system development
GO:0021766 - hippocampus development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1432921

BTNL2
Butyrophilin-like protein 2

1

4

High-throughput

0.691

High

380354

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

10

High-throughput

0.536

High

380485

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

1

12

High-throughput

0.536

High

568093

HLAE
HLA class I histocompatibility antigen, alpha chain E

1

2

High-throughput

0.536

High

593496

PGFRA
Platelet-derived growth factor receptor alpha

1

8

High-throughput

0.536

High

607418

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

2

High-throughput

0.536

High

627568

DPA1
HLA class II histocompatibility antigen, DP alpha 1 chain

1

10

High-throughput

0.536

High

1030214

IL5RA
Interleukin-5 receptor subunit alpha

1

3

High-throughput

0.536

High

1098939

KLRD1
Natural killer cells antigen CD94

1

11

High-throughput

0.536

High

1116302

PTC1
Protein patched homolog 1

1

8

High-throughput

0.536

High

1248584

LYPD4
Ly6/PLAUR domain-containing protein 4

1

1

High-throughput

0.536

High

1355999

CLC4C
C-type lectin domain family 4 member C

1

4

High-throughput

0.536

High

1363144

CLC2B
C-type lectin domain family 2 member B

1

11

High-throughput

0.536

High

1382060

T106A
Transmembrane protein 106A

1

4

High-throughput

0.536

High

1390879

ASIC4
Acid-sensing ion channel 4

1

1

High-throughput

0.536

High

1432923

PCDB3
Protocadherin beta-3

1

3

High-throughput

0.536

High

519662

LYAG
Lysosomal alpha-glucosidase

1

0

High-throughput

0.513

High

1036249

NRG1
Pro-neuregulin-1, membrane-bound isoform

1

0

High-throughput

0.513

High

1333775

TM87A
Transmembrane protein 87A

1

0

High-throughput

0.513

High

154883

ISLR
Immunoglobulin superfamily containing leucine-rich repeat protein

1

1

High-throughput

0.489

High

342665

LY86
Lymphocyte antigen 86

1

3

High-throughput

0.489

High

388741

C1QB
Complement C1q subcomponent subunit B

1

6

High-throughput

0.489

High

455665

KLK3
Prostate-specific antigen

1

10

High-throughput

0.489

High

548116

PSPC
Surfactant protein C

1

3

High-throughput

0.489

High

567980

PRG2
Bone marrow proteoglycan

1

6

High-throughput

0.489

High

597812

CRIS2
Cysteine-rich secretory protein 2

1

2

High-throughput

0.489

High

880065

DNSL1
Deoxyribonuclease-1-like 1

1

2

High-throughput

0.489

High

933225

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

3

High-throughput

0.489

High

935801

MFAP4
Microfibril-associated glycoprotein 4

1

2

High-throughput

0.489

High

976859

LCN6
Epididymal-specific lipocalin-6

1

3

High-throughput

0.489

High

1057114

FMOD
Fibromodulin

1

1

High-throughput

0.489

High

1432109

KLK15
Kallikrein-15

1

9

High-throughput

0.489

High

1432916

CST9L
Cystatin-9-like

1

4

High-throughput

0.489

High

1432917

SDF2L
Stromal cell-derived factor 2-like protein 1

1

5

High-throughput

0.489

High

1432918

CBLN4
Cerebellin-4

1

6

High-throughput

0.489

High

1432919

DNJB9
DnaJ homolog subfamily B member 9

1

5

High-throughput

0.489

High

1432922

FBX2
F-box only protein 2

1

9

High-throughput

0.489

High

1141932

EEA1
Early endosome antigen 1

1

3

High-throughput

0.437

High

170961

CLGN
Calmegin

1

4

High-throughput

0.407

High

191396

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

1

1

High-throughput

0.407

High

691425

1433T
14-3-3 protein theta

1

3

High-throughput

0.407

High

730235

1433B
14-3-3 protein beta/alpha

1

3

High-throughput

0.407

High

1258576

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

1

High-throughput

0.407

High

1194711

GXLT1
Glucoside xylosyltransferase 1

1

0

High-throughput

0.279

Low

1432920

DJB11
DnaJ homolog subfamily B member 11

1

0

High-throughput

0.279

Low

1396018

SMIM8
Small integral membrane protein 8

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025