Interactor 1: AXIN1 (O15169)
Axin-1 (Axis inhibition protein 1) (hAxin)
Gene: AXIN1

Interactor 2: PLAK (P14923)
Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3)
Gene: JUP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.66 1.00 0.817

The method score is based on:

Property Details
Experiments 26496610, 26871637
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, two hybrid array
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Arm~Axin_b-cat_bind
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0042803 - protein homodimerization activity
and 1 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 862
Hs

1 745
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
+ Mm
+ Dm
+ Mm

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Last updated: 15 Jul 2024