HitPredict

Interactor 1: PFD6 (O15212)
Prefoldin subunit 6 (Protein Ke2)
Gene: PFDN6

Interactor 2: PFD4 (Q9NQP4)
Prefoldin subunit 4 (Protein C-1)
Gene: PFDN4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.85	1.00	0.927

The method score is based on:

Property	Details
Experiments	24981860, 35271311, 28514442, 33961781, 34349018
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	Prefoldin_2~Prefoldin_2
Common GO terms	GO:0001540 - amyloid-beta binding GO:0005737 - cytoplasm GO:0006457 - protein folding GO:0016272 - prefoldin complex GO:0051082 - unfolded protein binding and 3 others more... GO:0051087 - protein-folding chaperone binding GO:0061077 - chaperone-mediated protein folding GO:1905907 - negative regulation of amyloid fibril formation
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	129
Hs

1	134

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024