HitPredict

Interactor 1: GSTA4 (O15217)
Glutathione S-transferase A4 (EC 2.5.1.18) (GST class-alpha member 4) (Glutathione S-transferase A4-4)
Gene: GSTA4

Interactor 2: GSTA1 (P08263)
Glutathione S-transferase A1 (EC 2.5.1.18) (13-hydroperoxyoctadecadienoate peroxidase) (EC 1.11.1.-) (Androst-5-ene-3,17-dione isomerase) (EC 5.3.3.-) (GST HA subunit 1) (GST class-alpha member 1) (GST-epsilon) (GSTA1-1) (GTH1) [Cleaved into: Glutathione S-transferase A1, N-terminally processed]
Gene: GSTA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	GST_C_3~GST_N, GST_C~GST_N, GST_N~GST_N
Common GO terms	GO:0004364 - glutathione transferase activity GO:0005829 - cytosol GO:0006749 - glutathione metabolic process GO:0006805 - xenobiotic metabolic process
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 222 Hs			1 222
+	Hs
		439287 Q5JW85_HUMAN (51-221): 2.92e-72: 218: 50.88		GSTA1_HUMAN (1-222): 2.01e-69: 213: 100.00
+	Hs
		448267 Q5JW85_HUMAN (51-221): 2.92e-72: 218: 50.88		GSTA2_HUMAN (1-222): 2.88e-68: 210: 95.05
+	Hs
		439286 GSTA3_HUMAN (1-221): 4.53e-65: 202: 53.39		GSTA1_HUMAN (1-222): 2.01e-69: 213: 100.00
+	Ce
		488050 P91505_CAEEL (6-206): 1.36e-72: 220: 23.27		GSTP1_CAEEL (6-210): 5.38e-62: 194: 26.57
+	Hs
		448266 GSTA3_HUMAN (1-221): 4.53e-65: 202: 53.39		GSTA2_HUMAN (1-222): 2.88e-68: 210: 95.05
+	Hs
		439277 GSTA1_HUMAN (1-221): 8.97e-64: 198: 53.85		GSTA1_HUMAN (1-222): 2.01e-69: 213: 100.00
+	Hs
		439278 GSTA2_HUMAN (1-221): 2.12e-63: 198: 54.30		GSTA1_HUMAN (1-222): 2.01e-69: 213: 100.00
+	Hs
		240490 HPGDS_HUMAN (5-205): 8.57e-65: 200: 23.15		HPGDS_HUMAN (5-205): 1.9e-68: 210: 25.12
+	Hs
		439289 GSTA1_HUMAN (1-221): 8.97e-64: 198: 53.85		GSTA5_HUMAN (1-222): 6.06e-66: 204: 90.09
+	Hs
		448268 GSTA2_HUMAN (1-221): 2.12e-63: 198: 54.30		GSTA5_HUMAN (1-222): 6.06e-66: 204: 90.09
+	Hs
		171872 GSTA2_HUMAN (1-221): 2.12e-63: 198: 54.30		GSTA4_HUMAN (1-221): 2.22e-58: 185: 53.85
+	Hs
		171874 GSTA5_HUMAN (1-221): 1.56e-61: 193: 53.39		GSTA4_HUMAN (1-221): 2.22e-58: 185: 53.85
+	Hs
		171868 GSTA4_HUMAN (1-222): 1.23e-60: 191: 100.00		GSTA4_HUMAN (1-221): 2.22e-58: 185: 53.85